Interstitial Cells of Cajal—Origin, Distribution and Relationship with Gastrointestinal Tumors [PDF]
Medicina, 2022 The interstitial cells of Cajal (ICC) represent a particular network formed by some peculiar cells that were first described by the great neuroanatomist, S. Ramon y Cajal.
Petru Radu +10 more
doaj +3 more sources
The Crucial Role of the Interstitial Cells of Cajal in Neurointestinal Diseases [PDF]
Biomolecules, 2023 Neurointestinal diseases result from dysregulated interactions between the nervous system and the gastrointestinal (GI) tract, leading to conditions such as Hirschsprung’s disease and irritable bowel syndrome.
Egan L. Choi +4 more
doaj +3 more sources
Interstitial cells of Cajal in gastrointestinal inflammatory diseases. [PDF]
J Smooth Muscle Res, 2023 The gastrointestinal (GI) tract is a vital organ that digests food, absorbs nutrients, and excretes waste. Normal GI motility is the basis for these functions.
Kaji N, Hori M.
europepmc +4 more sources
Propulsive colonic contractions are mediated by inhibition-driven poststimulus responses that originate in interstitial cells of Cajal. [PDF]
Proc Natl Acad Sci U S A, 2022 Significance The peristaltic reflex elicits colonic migrating motor complexes (CMMCs) that are thought to be generated by enteric excitatory neurons stimulating smooth muscle cells (SMCs).
Koh SD +14 more
europepmc +4 more sources
Interstitial cells of Cajal - pacemakers of the gastrointestinal tract. [PDF]
J Physiol, 2023 Gastrointestinal (GI) organs display spontaneous, non-neurogenic electrical, and mechanical rhythmicity that underlies fundamental motility patterns, such as peristalsis and segmentation.
Sanders KM, Santana LF, Baker SA.
europepmc +4 more sources
Interstitial cells of Cajal: clinical relevance in pediatric gastrointestinal motility disorders. [PDF]
Pediatr Surg Int, 2023 Interstitial cells of Cajal (ICCs) are pacemaker cells of gastrointestinal motility that generate and transmit electrical slow waves to smooth muscle cells in the gut wall, thus inducing phasic contractions and coordinated peristalsis.
Friedmacher F, Rolle U.
europepmc +2 more sources
Corrigendum: A bibliometric analysis of interstitial cells of Cajal research [PDF]
Frontiers in MedicinePengyu Li +7 more
doaj +4 more sources
Understanding the Biology of Human Interstitial Cells of Cajal in Gastrointestinal Motility
International Journal of Molecular Sciences, 2020 Millions of patients worldwide suffer from gastrointestinal (GI) motility disorders such as gastroparesis. These disorders typically include debilitating symptoms, such as chronic nausea and vomiting. As no cures are currently available, clinical care is
Daphne Foong, Jerry Zhou, Vincent Ho
exaly +2 more sources
Journal of Indian Association of Pediatric Surgeons, 2022 Introduction: The etiopathogenesis of pelviureteric junction obstruction (PUJO) has been debated. Recently, the role of interstitial cells of Cajal-like cells (ICC-LC) has been studied and reported to be the cause of this functional obstruction.
Ruchira Nandan +6 more
doaj +2 more sources