Results 91 to 100 of about 20,034 (267)

Identification and functional response of interstitial Cajal-like cells from rat mesenteric artery [PDF]

, 2018
Cells with irregular shapes, numerous long thin filaments, and morphological similarities to the gastrointestinal interstitial cells of Cajal (ICCs) have been observed in the wall of some blood vessels. These ICC-like cells (ICC-LCs) do not correspond to
Boittin, François-Xavier, Buscemi, Lara, Bény, Jean-Louis, Formey, Aurélie, Meister, Jean-Jacques   +4 more
core  

Microencapsulated Quercetin and Bifidobacterium animalis Independently Preserve Jejunal Enteric Neurons During Colorectal Carcinogenesis

Neurogastroenterology &Motility, EarlyView.
Our study explores the impact of colorectal carcinogenesis on jejunal neurons of the enteric nervous system (ENS), revealing significant neuronal damage. We demonstrated that treatments with microencapsulated quercetin and Bifidobacterium animalis protect enteric neuronal density, and this is reflected in improved gastrointestinal transit times.
Lucas Casagrande, Carla Cristina de Oliveira Bernardo, Sabrina Silva Sestak, Maysa Pacheco Alvarez da Silva, Marcos Yudi Nagaoka Godoy, Jean‐Pierre Timmermans, Cesar Agostinho Ferreira, Tânia Cristina Alexandrino Becker, Erick Guilherme Stoppa, Waldiceu Aparecido Verri, José Ricardo de Arruma Miranda, Juliana Vanessa Colombo Martins Perles, Jacqueline Nelisis Zanoni   +12 more
wiley   +1 more source

Mapping the variability of in vivo rat uterine electrical properties throughout the oestrous cycle

Experimental Physiology, EarlyView.
Abstract After reaching sexual maturity, uterine function is driven by cyclical variations in hormone levels. The electrical and mechanical activity in the uterus varies during the menstrual cycle, contributing to essential functions such as sperm transport and shedding the menstrual lining.
Mathias W. Roesler, Amy S. Garrett, Leo K. Cheng, Alys R. Clark   +3 more
wiley   +1 more source

Gastrointestinal Stromal Tumor (GIST) in Long Standing Crohn’s disease on Anti-TNF Therapy [PDF]

, 2020
Introduction Patients suffering from inflammatory bowel disease (IBD) are at increased risk for developing cancer. Adenocarcinomas are the most commonly observed tumors of the gastrointestinal tract whereas data on gastrointestinal stromal tumor (GIST ...
Davis, Brian, Lippman, H R, Mendel, David, Syed, Taseen   +3 more
core   +1 more source

Cells and ionic conductances contributing to spontaneous activity in bladder and urethral smooth muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Cells and conductances contributing to spontaneous activity in the lower urinary tract. Bladder and urethra exhibit spontaneous contractions at both cellular and tissue levels. Both detrusor and urethral smooth muscle cells display activity that is regular and rhythmic.
Bernard T. Drumm, Neha Gupta, Alexandru Mircea, Caoimhin S. Griffin   +3 more
wiley   +1 more source

CT features, mimics and atypical presentations of gastrointestinal stromal tumor (GIST)

Indian Journal of Radiology and Imaging, 2011
The term stromal tumor was coined in 1983 by Clark and Mazur for smooth muscle neoplasm of the gastrointestinal tract (GIT). Gastrointestinal stromal tumors (GIST) are nonepithelial tumors arising from the interstitial cells of Cajal, which express KIT ...
Smiti Sripathi, KV Rajagopal, Rajendra Kumar Srivastava, Anurag Ayachit   +3 more
doaj   +1 more source

An update on pacemaking in the myometrium

The Journal of Physiology, EarlyView.
Abstract figure legend The spread of multiple electrical signals (panel A, blue‐to‐red indicates increasing electrical excitability) that are spatiotemporally distinct, yet in‐phase with the excitatory episode, determines action potential shape and form (panel B, as recorded by single cell microelectrodes) and ensures contractile amplitude and duration
Susan Wray, Michael J. Taggart
wiley   +1 more source

The effect of high [K(+)]o on spontaneous Ca(2+) waves in freshly isolated interstitial cells of Cajal from the rabbit urethra. [PDF]

, 2014
Interstitial cells of Cajal (ICC) act as putative pacemaker cells in the rabbit urethra. Pacemaker activity in ICC results from spontaneous global Ca(2+) waves that can be increased in frequency by raising external [K(+)].
Baba, Akemichi, Drumm, Bernard T, Harvey, Brian J, Hollywood, Mark A, Matsuda, Toshio T, McHale, Noel G, Sergeant, Gerard P, Thornbury, Keith T   +7 more
core   +1 more source

Piezo1 in intestinal smooth muscle cells: Emerging perspectives

The Journal of Physiology, EarlyView.
Abstract figure legend Loss of Piezo1 in SMCs results in delayed gut transit, impaired small bowel contractility, and tissue alterations. But more critically, Piezo1 is shown to be intracellularly localized, highlighting important implications given the phenotype. Adapted from Bautista, G.M. et al.
Geoanna M. Bautista, L. Fernando Santana, Martin G. Martin   +2 more
wiley   +1 more source

Hesperidin depolarizes the pacemaker potentials through 5-HT4 receptor in murine small intestinal interstitial cells of Cajal

Animal Cells and Systems, 2020
Hesperidin, a citrus flavonoid, can exert numerous beneficial effects on human health. Interstitial cells of Cajal (ICC) are pacemaker cells in the gastrointestinal (GI) tract.
Minwoo Hwang, Jeong Nam Kim, Byung Joo Kim   +2 more
doaj   +1 more source