Role of Cytolethal Distending Toxin in Altered Stool Form and Bowel Phenotypes in a Rat Model of Post-infectious Irritable Bowel Syndrome. [PDF]
, 2012 Background/aimsCampylobacter jejuni infection is a leading cause of acute gastroenteritis, which is a trigger for post-infectious irritable bowel syndrome (PI-IBS). Cytolethal distending toxin (CDT) is expressed by enteric pathogens that cause PI-IBS. We
Alpern, Joel +12 more
core +1 more source
Cellular and Molecular Gastroenterology and Hepatology, 2023 Background & Aims: Impaired gastric motor function in the elderly causes reduced food intake leading to frailty and sarcopenia. We previously found that aging-related impaired gastric compliance was mainly owing to depletion of interstitial cells of ...
Vy Truong Thuy Nguyen +5 more
doaj +1 more source
C-kit receptor immunopositive interstitial cells (Cajal-type) in the porcine reproductive tract
Acta Veterinaria Scandinavica, 2017 Background Interstitial Cajal cells have been suspected as being the pacemaker cells of smooth muscle motor activity and discharging slow triggering waves in the gut as well as in other organs containing smooth muscles where they are known as ...
Malgorzata Domino +3 more
doaj +1 more source
Changes in interstitial cells and gastric excitability in a mouse model of sleeve gastrectomy.
PLoS ONE, 2022 Obesity is a critical risk factor of several life-threatening diseases and the prevalence in adults has dramatically increased over the past ten years.
Suk Bae Moon +7 more
doaj +1 more source
Muscarinic M2 acetylcholine receptor distribution in the guinea-pig gastrointestinal tract [PDF]
, 2006 In the enteric nervous system, acetylcholine is the most common neurotransmitter to induce gastrointestinal smooth muscle contractions. Cholinergic signaling is mediated by muscarinic acetylcholine receptors on the surface of smooth muscle cells.
58998 +3 more
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Telocytes and Lymphatics of the Human Colon
Life, 2021 Background: Telocytes (TCs) are a peculiar morphological type of stromal cells. They project long and moniliform telopodes, visible on various bidimensional sections. Originally regarded as “interstitial Cajal-like cells”, gastrointestinal TCs were CD34+.
Mihai Zurzu +4 more
doaj +1 more source
Transcriptome profiling reveals significant changes in the gastric muscularis externa with obesity that partially overlap those that occur with idiopathic gastroparesis [PDF]
, 2019 BACKGROUND: Gastric emptying is impaired in patients with gastroparesis whereas it is either unchanged or accelerated in obese individuals. The goal of the current study was to identify changes in gene expression in the stomach muscularis that may be ...
Chen, Meng +7 more
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Resident phenotypically modulated vascular smooth muscle cells in healthy human arteries. [PDF]
, 2012 Vascular interstitial cells (VICs) are non-contractile cells with filopodia previously described in healthy blood vessels of rodents and their function remains unknown.
Greenwood, IA +10 more
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Interstitial cell network volume is reduced in the terminal bowel of ageing mice [PDF]
, 2018 Ageing is associated with impaired neuromuscular function of the terminal gastrointestinal (GI) tract, which can result in chronic constipation, faecal impaction and incontinence.
Gamage, Prasanna P. K. M. +4 more
core +3 more sources