Results 211 to 220 of about 900,542 (272)
Phytotherapy Research, EarlyView.Proposed mechanism by which notoginsenoside R2 (NGR2) attenuates renal interstitial fibrosis. In injured renal tubular epithelial cells, CASP2 downregulation and enhanced ubiquitin‐dependent degradation of ALDH3A1 disrupt mitochondria‐associated endoplasmic reticulum membranes (MAMs) and impair fatty acid oxidation (FAO), leading to lipid accumulation ...
Guanting Chen +10 more
wiley +1 more source
Small, EarlyView.ABSTRACT Active and stable electrocatalysts are critical for sustainable hydrogen production, particularly for high‐current‐density water electrolysis and specialized applications like seawater splitting. However, most water‐splitting electrocatalysts show limited activity at high current densities and poor long‐term stability, making it difficult to ...
Nikhil Komalla, Nelson Y. Dzade
wiley +1 more source
Exploring Phenotype-Genotype Correlations Using Interstitial Glucose Results in a Family With a Glucokinase Mutation. [PDF]
J Diabetes Sci Technol, 2018 Lunt H, Heenan H, Chan H.
europepmc +1 more source
Small, EarlyView.A tiered nanoporous gold biointerface enables site‐directed immobilization of His‐tagged lactate oxidase through a mixed self‐assembled monolayer, achieving high enzyme loading while preserving activity. The resulting bioelectrode provides sensitive and stable l‐lactate detection (0.12–3.0 mM, 75 µA mM−1 cm−2), demonstrating a modular strategy for high‐
Mislav Sušac +6 more
wiley +1 more source
Small, EarlyView.A multimodal multiphoton imaging framework enables high‐resolution quantification of water diffusion in brain tissue. By tracking deuterated water via stimulated Raman scattering (SRS) microscopy, this study resolves the microscopic heterogeneity of water diffusion at cellular resolution and determines apparent diffusion coefficients in health and ...
Wakana Ozaki +4 more
wiley +1 more source
Small, EarlyView.Schematic illustration of the construction of MM‐NTU, its cardiac‐targeting behavior, and its light‐activated therapeutic mechanism. Thylakoids isolated from spinach chloroplasts were processed into nano‐thylakoid units (NTU) and further camouflaged with cardiomyocyte membranes to generate MM‐NTU.
Haohui Fan +13 more
wiley +1 more source
How Much Accuracy of Interstitial Glucose Measurement Is Enough? Is There a Need for New Evidence? [PDF]
J Diabetes Sci Technol, 2017 Hermanns N, Ehrmann D, Kulzer B.
europepmc +1 more source
Fenestrated Microneedle Biosensor for Continuous In Vivo Lactate Monitoring in Interstitial Fluid
Small, EarlyView.A fenestrated microneedle biosensor enables continuous transdermal monitoring of lactate in interstitial fluid while protecting the functional sensing interface during insertion into the skin. The platform delivers sensitive electrochemical lactate detection and distinguishes metabolic profiles in healthy and type 2 diabetic‐obese mice, and captures ...
Masoud Khazaei +5 more
wiley +1 more source
Smart Molecules, EarlyView.Smart mesoporous silica nanoparticles integrate tunable pore structures, molecular gates, targeting ligands, and stimuli‐responsive components to achieve controlled drug release for precision cancer therapy. This review highlights design principles, therapeutic applications, and future directions in immunotherapy, biodegradability, biosafety, and ...
Majdi Al‐Amili, Lei Lei, Zhu Jin
wiley +1 more source
Progress in bone tissue engineering biomaterials: Development, challenges, and prospects
VIEW, EarlyView.Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang +7 more
wiley +1 more source