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A Microscopic, Continous, Optical Monitor for Interstitial Electrolytes and Glucose

ChemPhysChem, 2003
AbstractIons, such as hydrogen (pH), sodium, or potassium, as well as metabolites, such as glucose or lactate, diffuse easily between blood in the capillaries and the interstitial fluid (ISF) residing between cells and tissues. This work represents a synthesis of several unique concepts to achieve accurate, continuous, in vivo monitoring of critical ...
Koji, Tohda, Miklós, Gratzl
openaire   +2 more sources

Interstitial Glucose Prediction Improvement Through Wearable-Derived Features

Fil: Ferrández, Juan Manuel.
Hongn, Andrea   +3 more
openaire   +2 more sources

Validation of Interstitial Fluid Continuous Glucose Monitoring in Cystic Fibrosis

Diabetes Care, 2003
Diabetes is a complication of cystic fibrosis (CF) that is of growing clinical importance. The recognition of diabetes complications in CF subjects (1) has emphasized the need for more accurate monitoring of glycemia. This is complicated by the many factors affecting glycemia in CF subjects, ranging from the consequences of malabsorption to the caloric
Lee, Dobson   +2 more
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Decreased interstitial glucose and transmural gradient in lactate during ischemia

Basic Research in Cardiology, 1994
The purpose of this investigation was to assess the effects of ischemia and reperfusion on the transmural levels of glucose and lactate in the interstitium in 11 open-chest swine. Microdialysis probes were used to estimate changes in interstitial metabolities across the ventricular wall. Probes were placed in the subepicardium and the subendocardium of
J L, Hall   +4 more
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Cinnamaldehyde impairs high glucose-induced hypertrophy in renal interstitial fibroblasts

Toxicology and Applied Pharmacology, 2010
Cinnamaldehyde is a major and a bioactive compound isolated from the leaves of Cinnamomum osmophloeum kaneh. To explore whether cinnamaldehyde was linked to altered high glucose (HG)-mediated renal tubulointerstitial fibrosis in diabetic nephropathy (DN), the molecular mechanisms of cinnamaldehyde responsible for inhibition of HG-induced hypertrophy in
Louis Kuoping, Chao   +3 more
openaire   +2 more sources

Diurnal correlation of ambulatory blood pressure and interstitial glucose in patients with normal glucose tolerance

Blood Pressure Monitoring, 2008
Among the physiological variables whose diurnal profile is governed by circadian rhythmicity, plasma glucose concentrations, and arterial blood pressure constitute key elements of the physiological regulation of energy homeostasis. Evidence on their diurnal association derived from frequent measurements of both variables is, however, lacking in humans ...
Nikolaos A, Zakopoulos   +10 more
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Optical microsensor for continuous glucose measurements in interstitial fluid

SPIE Proceedings, 2006
Tight control of blood glucose levels has been shown to dramatically reduce the long-term complications of diabetes. Current invasive technology for monitoring glucose levels is effective but underutilized by people with diabetes because of the pain of repeated finger-sticks, the inconvenience of handling samples of blood, and the cost of reagent ...
Jonathon T. Olesberg   +7 more
openaire   +1 more source

Continuous glucose monitoring in interstitial fluid using glucose oxidase-based sensor compared to established blood glucose measurement in rats

Analytica Chimica Acta, 2007
Glucose monitoring is of importance for success of complex therapeutic interventions in diabetic patients. Its impact on treatment and glycemic control is demonstrated in large clinical trials. Up to eight blood glucose measurements per day are recommended.
Stefanie, Woderer   +8 more
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Closed-Loop Interstitial Fluid Sensing Continuous Glucose Monitor

2016
At present, the food and drug administration (FDA) has not approved any fully implantable continuous glucose monitors (CGMs). Currently, diabetes patients cannot adjust the insulin dose their body needs solely based on readings made from CGMs. The FDA has only approved the use of CGMs as supplements, not replacements, to home blood glucose meters that ...
openaire   +1 more source

Wearable filamentary continuous sensor for interstitial glucose detection in diabetes management

Analytica Chimica Acta
The development of novel diabetes monitoring sensors is important for the diabetes management of millions of diabetic patients. This work reports a flexible filamentary continuous glucose monitoring (CGM) sensor. A multilayer CGM sensor has been constructed on titanium filament with low cost and ease of use.
Changxi Zhang   +3 more
openaire   +2 more sources

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