Results 171 to 180 of about 182,063 (264)

Nanoagonist‐mediated spatiotemporal reprogramming of macrophage phenotypes to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes the major molecular mechanisms governing TAM polarization and their coordinated interactions. It further highlights recent advances in nanoagonist‐based strategies that intervene in these pathways to reprogram TAMs, critically discussing their therapeutic potential, current limitations, and translational prospects.
Siqi Fang, Fengfeng Xiao, Ruie Chen, Cuixia Lu, Yi Ju, Mingqing Yuan, Yunlu Dai, Liewei Wen   +7 more
wiley   +1 more source

Advances in pharmacotherapy for fibrotic interstitial lung disease. [PDF]

Med Rev (2021)
Feng X, Deng M, Miao J, Zheng Z, Hou G.
europepmc   +1 more source

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

Chemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi, Alessandro Rubbi, Pablo A. Nogara, Giovanni Ribaudo, Vito Lippolis, João B. T. Rocha, Laura Orian   +6 more
wiley   +1 more source

Prevalence and screening of interstitial lung disease in rheumatoid arthritis. [PDF]

Rheumatol Adv Pract
Gono T.
europepmc   +1 more source

Intelligent Automation Improved Efficiency in Pharmacovigilance Safety Signal Assessment

Clinical Pharmacology &Therapeutics, EarlyView.
Pharmacovigilance is the science involving the detection, assessment, understanding, and prevention of adverse events associated with drugs, biologics, or medical devices. In pharmacovigilance, information that suggests a new potential causal relationship between an intervention and an adverse event is called a safety signal. Following their detection,
Jeffrey Warner, Luis Henrique De Souza Teodoro, Anaclara Prada Jardim, Claudia Albera   +3 more
wiley   +1 more source

Diaphragmatic Ultrasound in Fibrosing Interstitial Lung Disease: A Systematic Review of Current Evidence. [PDF]

Diagnostics (Basel)
Patabendige S, Falster C, Langkilde HZ, Harders SMW, Bendstrup E, Skaarup SH, Durheim MT, Davidsen JR.   +7 more
europepmc   +1 more source

Ulcerated Gottron's papules in anti‐MDA5 dermatomyositis

Arthritis &Rheumatology, Accepted Article.
Philipp Jud, Monica D'Orazio
wiley   +1 more source

Toward Fit‐for‐Purpose Data for Drug Assessment in Non‐small Cell Lung Cancer: A Core Dataset

Clinical Pharmacology &Therapeutics, EarlyView.
Considering the high unmet medical need in people with non‐small cell lung cancer (NSCLC), the drug assessment for targeted therapies often rely on small populations and single‐arm trials, challenging the evaluation by regulatory authorities, health technology assessment bodies (HTAb), and clinicians.
Geeske F. Grit, Maaike van Dartel, Laura Rodwell, Hanneke van der Woude, Cornelis Boersma, Peter G. M. Mol, Doranne Hilarius   +6 more
wiley   +1 more source

Analysis of Factors Associated With Interstitial Lung Disease in Treatment-Naïve Rheumatoid Arthritis Patients and Development of a Classification Nomogram. [PDF]

Immun Inflamm Dis
Lu L, Chen Y, Zhang T, Cao L, Ma H, Song Y, Zhou D.   +6 more
europepmc   +1 more source