Results 181 to 190 of about 754,612 (422)

Animal models of lung cancer: Phenotypic comparison of different animal models of lung cancer and their application in the study of mechanisms

Animal Models and Experimental Medicine, EarlyView.
Grafts used to construct lung cancer animal models come from various sources, primarily cell lines, patient‐derived tumor tissues, and circulating tumor cells. Based on the sources of grafts and research objectives, lung cancer animal models can be categorized into several types: chemical‐induced models, orthotopic transplantation models, heterotopic ...
Zixuan Yang, Xianbin Zhao, Lili Tan, Pingxinyi Que, Tong Zhao, Wei Huang, Dejiao Yao, Songqi Tang   +7 more
wiley   +1 more source

Multi-center evaluation of baseline neutrophil-to-lymphocyte (NLR) ratio as an independent predictor of mortality and clinical risk stratifier in idiopathic pulmonary fibrosisResearch in context

EClinicalMedicine, 2023
Summary: Background: Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal disorder with a variable disease trajectory. The aim of this study was to assess the potential of neutrophil-to-lymphocyte ratio (NLR) to predict outcomes in IPF.
Theresia A. Mikolasch, Peter M. George, Jagdeep Sahota, Thomas Nancarrow, Shaney L. Barratt, Felix A. Woodhead, Vasilis Kouranos, Victoria S.A. Cope, Andrew W. Creamer, Silan Fidan, Balaji Ganeshan, Luke Hoy, John A. Mackintosh, Robert Shortman, Anna Duckworth, Janet Fallon, Helen Garthwaite, Melissa Heightman, Huzaifa I. Adamali, Sarah Lines, Thida Win, Rebecca Wollerton, Elisabetta A. Renzoni, Matthew Steward, Athol U. Wells, Michael Gibbons, Ashley M. Groves, Bibek Gooptu, Chris J. Scotton, Joanna C. Porter   +29 more
doaj  

Evaluating disease severity in idiopathic pulmonary fibrosis

European Respiratory Review, 2017
Accurate assessment of idiopathic pulmonary fibrosis (IPF) disease severity is integral to the care provided to patients with IPF. However, to date, there are no generally accepted or validated staging systems.
Hasti Robbie, Cécile Daccord, Felix Chua, Anand Devaraj   +3 more
doaj   +1 more source

Interactive user interface based on Convolutional Auto-encoders for annotating CT-scans [PDF]

arXiv, 2019
High resolution computed tomography (HRCT) is the most important imaging modality for interstitial lung diseases, where the radiologists are interested in identifying certain patterns, and their volumetric and regional distribution. The use of machine learning can assist the radiologists with both these tasks by performing semantic segmentation.
arxiv  

Production of fibronectin by the human alveolar macrophage: mechanism for the recruitment of fibroblasts to sites of tissue injury in interstitial lung diseases. [PDF]

, 1981
S. I. Rennard, Gary W. Hunninghake, Peter B. Bitterman, Ronald G. Crystal   +3 more
openalex   +1 more source

Comparison of the pathogenicity of multiple SARS‐CoV‐2 variants in mouse models

Animal Models and Experimental Medicine, EarlyView.
We assessed the pathogenicity of various SARS‐CoV‐2 variants using two distinct mouse models. Our findings indicated that earlier variants, including WH‐09, Beta, and Delta, exhibited greater pathogenicity than later variants. Specifically, the Omicron variant demonstrated reduced pathogenicity, characterized by a shorter disease course and diminished ...
Qi Lv, Ming Liu, Feifei Qi, Mingya Liu, Fengdi Li, Ran Deng, Xujian Liang, Yanfeng Xu, Zhiqi Song, Yiwei Yan, Shuyue Li, Guocui Mou, Linlin Bao   +12 more
wiley   +1 more source

Angiotropic large cell lymphoma presenting as interstitial lung disease. [PDF]

, 1988
Tulip Tan, P. Spaander, M Blaisse, F M Gerritzen   +3 more
openalex   +1 more source

Advances in CRISPR‐Cas9 in lineage tracing of model animals

Animal Models and Experimental Medicine, EarlyView.
Cell lineage tracing is a key technology for describing the developmental history of individual progenitor cells and assembling them to form a lineage development tree. However, traditional methods have limitations of poor stability and insufficient resolution.
Jingchao Cao, Zihang Guo, Xueling Xu, Pan Li, Yi Fang, Shoulong Deng   +5 more
wiley   +1 more source

Noninvasive Assessment of Cardiovascular Performance in Interstitial and Chronic Obstructive Lung Disease [PDF]

, 1984
Richard A. Matthay, Jacob Loke
openalex   +1 more source

Distinct Alterations of Inflammatory Biomarkers in Cluster Headache: A Case Control Study

Annals of Neurology, EarlyView.
Objective Investigate the immune system's role in cluster headache by analyzing cytokines in people with cluster headache and headache‐free controls, and explore if certain cytokines could predict a specific phenotype. Methods We measured 45 cytokines in adult participants from the Danish Cluster Headache Biobank in a prospective case–control setup ...
Nunu Laura Timotheussen Lund, Connar Stanley James Westgate, Marie‐Louise Kulas Søborg, Agneta Henriette Snoer, Rigmor Højland Jensen, Thomas Folkman Hansen, Anja Sofie Petersen   +6 more
wiley   +1 more source