Results 181 to 190 of about 754,612 (422)

Animal models of lung cancer: Phenotypic comparison of different animal models of lung cancer and their application in the study of mechanisms

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Grafts used to construct lung cancer animal models come from various sources, primarily cell lines, patient‐derived tumor tissues, and circulating tumor cells. Based on the sources of grafts and research objectives, lung cancer animal models can be categorized into several types: chemical‐induced models, orthotopic transplantation models, heterotopic ...
Zixuan Yang   +7 more
wiley   +1 more source

Multi-center evaluation of baseline neutrophil-to-lymphocyte (NLR) ratio as an independent predictor of mortality and clinical risk stratifier in idiopathic pulmonary fibrosisResearch in context

open access: yesEClinicalMedicine, 2023
Summary: Background: Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal disorder with a variable disease trajectory. The aim of this study was to assess the potential of neutrophil-to-lymphocyte ratio (NLR) to predict outcomes in IPF.
Theresia A. Mikolasch   +29 more
doaj  

Evaluating disease severity in idiopathic pulmonary fibrosis

open access: yesEuropean Respiratory Review, 2017
Accurate assessment of idiopathic pulmonary fibrosis (IPF) disease severity is integral to the care provided to patients with IPF. However, to date, there are no generally accepted or validated staging systems.
Hasti Robbie   +3 more
doaj   +1 more source

Interactive user interface based on Convolutional Auto-encoders for annotating CT-scans [PDF]

open access: yesarXiv, 2019
High resolution computed tomography (HRCT) is the most important imaging modality for interstitial lung diseases, where the radiologists are interested in identifying certain patterns, and their volumetric and regional distribution. The use of machine learning can assist the radiologists with both these tasks by performing semantic segmentation.
arxiv  

Comparison of the pathogenicity of multiple SARS‐CoV‐2 variants in mouse models

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We assessed the pathogenicity of various SARS‐CoV‐2 variants using two distinct mouse models. Our findings indicated that earlier variants, including WH‐09, Beta, and Delta, exhibited greater pathogenicity than later variants. Specifically, the Omicron variant demonstrated reduced pathogenicity, characterized by a shorter disease course and diminished ...
Qi Lv   +12 more
wiley   +1 more source

Advances in CRISPR‐Cas9 in lineage tracing of model animals

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Cell lineage tracing is a key technology for describing the developmental history of individual progenitor cells and assembling them to form a lineage development tree. However, traditional methods have limitations of poor stability and insufficient resolution.
Jingchao Cao   +5 more
wiley   +1 more source

Distinct Alterations of Inflammatory Biomarkers in Cluster Headache: A Case Control Study

open access: yesAnnals of Neurology, EarlyView.
Objective Investigate the immune system's role in cluster headache by analyzing cytokines in people with cluster headache and headache‐free controls, and explore if certain cytokines could predict a specific phenotype. Methods We measured 45 cytokines in adult participants from the Danish Cluster Headache Biobank in a prospective case–control setup ...
Nunu Laura Timotheussen Lund   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy