Development of a Physiologically Based Pharmacokinetic (PBPK) Simulation Model for Nicotine
This study developed a region‐specific PBPK model for nicotine integrating various administration routes and lung compartments, validated using clinical PK data. This model enables an accurate prediction of nicotine kinetics and supports dose optimization for safer nicotine delivery systems. ABSTRACT Tobacco is a major cause of chronic diseases such as
Brian Kim +8 more
wiley +1 more source
CGR 10: RAPIDLY PROGRESSIVE INTERSTITIAL LUNG DISEASE ASSOCIATED WITH MDA‐5 ANTIBODIES [PDF]
Brittany Stevenson +2 more
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HIV-1 and SIV Infection are associated with early loss of lung interstitial CD4+ T cells and dissemination of pulmonary tuberculosis [PDF]
et al,, Khader, Shabaana A
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The PCLA‐SNP scaffolds can produce photothermal agents in situ under ultraviolet radiation. Then, the scaffold can release nitric oxide gas spontaneously and generate hyperthermia under near‐infrared laser to enhance ablation of bone tumors. Furthermore, the calcium and iron ions released from PCLA‐SNP scaffolds can accelerate bone regeneration ...
Shaojie Dong +9 more
wiley +1 more source
A case of antisynthetase syndrome with interstitial lung disease in pregnancy. [PDF]
Park E +3 more
europepmc +1 more source
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu +9 more
wiley +1 more source
Interstitial Lung Disease Secondary to Sjogren's Syndrome and Antisynthetase Syndrome: Converging Disease Trajectories. [PDF]
Muscato G +9 more
europepmc +1 more source
Serum cytokine profiles of patients with interstitial lung disease associated with anti-CADM-140/MDA5 antibody positive amyopathic dermatomyositis [PDF]
Toshinori Takada +6 more
openalex +1 more source
Fiber‐type soft bioelectronics for wearable and implantable sensing and therapy
Fiber‐type soft bioelectronics are emerging as versatile platforms for wearable and implantable health monitoring and therapeutic applications. These bioelectronics use organic and inorganic matrices combined with advanced fillers, which feature high conductivity, electrochemical sensitivity, softness, and biocompatibility.
Haneul Kim +5 more
wiley +1 more source

