Results 271 to 280 of about 774,384 (405)

Development of a Physiologically Based Pharmacokinetic (PBPK) Simulation Model for Nicotine

open access: yesBiopharmaceutics &Drug Disposition, EarlyView.
This study developed a region‐specific PBPK model for nicotine integrating various administration routes and lung compartments, validated using clinical PK data. This model enables an accurate prediction of nicotine kinetics and supports dose optimization for safer nicotine delivery systems. ABSTRACT Tobacco is a major cause of chronic diseases such as
Brian Kim   +8 more
wiley   +1 more source

The effect of sodium nitroprusside in scaffolds for synergetic gas‐photothermal therapy of osteosarcoma

open access: yesBMEMat, EarlyView.
The PCLA‐SNP scaffolds can produce photothermal agents in situ under ultraviolet radiation. Then, the scaffold can release nitric oxide gas spontaneously and generate hyperthermia under near‐infrared laser to enhance ablation of bone tumors. Furthermore, the calcium and iron ions released from PCLA‐SNP scaffolds can accelerate bone regeneration ...
Shaojie Dong   +9 more
wiley   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

open access: yesBMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu   +9 more
wiley   +1 more source

Interstitial Lung Disease Secondary to Sjogren's Syndrome and Antisynthetase Syndrome: Converging Disease Trajectories. [PDF]

open access: yesMedicina (Kaunas)
Muscato G   +9 more
europepmc   +1 more source

Serum cytokine profiles of patients with interstitial lung disease associated with anti-CADM-140/MDA5 antibody positive amyopathic dermatomyositis [PDF]

open access: bronze, 2015
Toshinori Takada   +6 more
openalex   +1 more source

Fiber‐type soft bioelectronics for wearable and implantable sensing and therapy

open access: yesBMEMat, EarlyView.
Fiber‐type soft bioelectronics are emerging as versatile platforms for wearable and implantable health monitoring and therapeutic applications. These bioelectronics use organic and inorganic matrices combined with advanced fillers, which feature high conductivity, electrochemical sensitivity, softness, and biocompatibility.
Haneul Kim   +5 more
wiley   +1 more source

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