Results 31 to 40 of about 734,704 (283)

Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease. An International Multicenter Study

American Journal of Respiratory and Critical Care Medicine, 2020
Rationale: The impact of coronavirus disease (COVID-19) on patients with interstitial lung disease (ILD) has not been established. Objectives: To assess outcomes in patients with ILD hospitalized for COVID-19 versus those without ILD in a contemporaneous
T. Drake, A. Docherty, E. Harrison, J. Quint, H. Adamali, S. Agnew, S. Babu, C. Barber, S. Barratt, E. Bendstrup, S. Bianchi, D. C. Villegas, N. Chaudhuri, F. Chua, R. Coker, William H. Chang, A. Crawshaw, Louise E. Crowley, D. Dosanjh, C. Fiddler, I. Forrest, P. George, Michael A. Gibbons, K. Groom, S. Haney, S. Hart, E. Heiden, M. Henry, L. Ho, R. Hoyles, J. Hutchinson, K. Hurley, Mark G. Jones, S. Jones, M. Kokosi, M. Kreuter, L. S. Mackay, S. Mahendran, G. Margaritopoulos, M. Molina-Molina, P. Molyneaux, A. O’Brien, K. O'Reilly, A. Packham, H. Parfrey, V. Poletti, J. Porter, E. Renzoni, P. Rivera-Ortega, A. Russell, G. Saini, L. Spencer, G. Stella, H. Stone, S. Sturney, D. Thickett, M. Thillai, T. Wallis, K. Ward, A. Wells, A. West, M. Wickremasinghe, F. Woodhead, G. Hearson, Lucy Howard, J. Baillie, P. Openshaw, M. Semple, I. Stewart, R. Jenkins, J. Baillie, M. Semple, P. Openshaw, G. Carson, B. Alex, Benjamin Bach, W. Barclay, D. Bogaert, M. Chand, Graham S. Cooke, A. Docherty, J. Dunning, A. da Silva Filipe, T. Fletcher, C. A. Green, E. Harrison, J. Hiscox, A. Ho, P. Horby, S. Ijaz, S. Khoo, P. Klenerman, Andrew Law, W. Lim, A. Mentzer, L. Merson, A. Meynert, M. Noursadeghi, S. Moore, M. Palmarini, W. Paxton, G. Pollakis, NicholasS . C. Price, A. Rambaut, David L. Robertson, C. Russell, V. Sancho-Shimizu, J. Scott, T. D. de Silva, L. Sigfrid, Tommy Solomon, S. Sriskandan, D. Stuart, C. Summers, R. Tedder, E. Thomson, A. Thompson, R. Thwaites, L. Turtle, M. Zambon, H. Hardwick, C. Donohue, Ruth-Marie Lyons, Fiona Griffiths, W. Oosthuyzen, L. Norman, R. Pius, Tom M. Drake, C. Fairfield, S. Knight, K. Mclean, D. Murphy, C. A. Shaw, Joanne Dalton, M. Girvan, Eglė Savičiūtė, S. Roberts, Janet R Harrison, Laura Marsh, M. Connor, S. Halpin, C. Jackson, C. Gamble, G. Leeming, Murray Wham, S. Clohisey, Ross Hendry, James Scott-Brown, W. Greenhalf, V. Shaw, Sarah E. McDonald, Sean S. Keating, K. Ahmed, J. Armstrong, M. Ashworth, I. G. Asiimwe, S. Bakshi, S. Barlow, Laura J. Booth, B. Brennan, K. Bullock, Benjamin W. A. Catterall, Jordan J. Clark, Emily Clarke, Sarah J. Cole, L. Cooper, H. Cox, Christopher Davis, Oslem Dincarslan, Chris Dunn, P. Dyer, A. Elliott, A. Evans, L. Finch, Lewis W. S. Fisher, T. Foster, Isabel García-Dorival, W. Greenhalf, P. Gunning, Catherine Hartley, A. Ho, R. L. Jensen, Christopher Jones, T. R. Jones, Shadia Khandaker, K. King, Robyn T Kiy, Chrysa Koukorava, Annette Lake, S. Lant, D. Latawiec, L. Lavelle-Langham, Daniella A. Lefteri, Lauren Lett, Lucia A. Livoti, Maria Mancini, L. McEvoy, J. Mclauchlan, S. Metelmann, N. Miah, J. Middleton, Joyce Mitchell, S. Moore, E. Murphy, R. Penrice-Randal, J. Pilgrim, T. Prince, W. Reynolds, P. Ridley, Debby Sales, V. Shaw, R. Shears, B. Small, Krishanthi S Subramaniam, Agnieska Szemiel, Aislynn Taggart, J. Tanianis-Hughes, Jordan Thomas, E. Trochu, Libby van Tonder, E. Wilcock, J. E. Zhang, K. Adeniji, D. Agranoff, K. Agwuh, D. Ail, A. Alegria, Brian Angus, A. Ashish, Doug Atkinson, S. Bari, G. Barlow, S. Barnass, Nicholas A. Barrett, C. Bassford, D. Baxter, M. Beadsworth, J. Bernatoniene, J. Berridge, N. Best, P. Bothma, D. Brealey, R. Brittain-Long, N. Bulteel, Thomas G Burden, A. Burtenshaw, Vikki Caruth, D. Chadwick, D. Chambler, Nigel Chee, J. Child, S. Chukkambotla, Tom Clark, P. Collini, Catherine Cosgrove, J. Cupitt, Maria-Teresa Cutino-Moguel, P. Dark, Chris Dawson, S. Dervisevic, P. Donnison, S. Douthwaite, I. DuRand, A. Dushianthan, Tristan Dyer, C. Evans, C. Eziefula, Chrisopher Fegan, A. Finn, D. Fullerton, S. Garg, A. Garg, E. Gkrania-Klotsas, J. Godden, A. Goldsmith, Clive Graham, E. Hardy, S. Hartshorn, D. Harvey, P. Havalda, D. Hawcutt, M. Hobrok, L. Hodgson, Anita Holme, A. Hormis, M. Jacobs, Susan Jain, P. Jennings, A. Kaliappan, V. Kasipandian, S. Kegg, Michael R. Kelsey, J. Kendall, C. Kerrison, I. Kerslake, O. Koch, G. Koduri, G. Koshy, S. Laha, S. Laird, Susan G. Larkin, T. Leiner, P. Lillie, James Limb, V. Linnett, J. Little, M. MacMahon, E. Macnaughton, Ravish Mankregod, Huw Masson, E. Matovu, K. McCullough, R. Mcewen, M. Meda, G. Mills, J. Minton, M. Mirfenderesky, K. Mohandas, Quen Mok, J. Moon, Elinoor Moore, P. Morgan, C. Morris, Katherine Mortimore, S. Moses, Mbiye A Mpenge, R. Mulla, Michael J. Murphy, Megan L. Nagel, T. Nagarajan, M. Nelson, I. Otahal, M. Pais, S. Panchatsharam, Hassan Paraiso, B. Patel, J. Pepperell, M. Peters, M. Phull, S. Pintus, J. Pooni, F. Post, D. Price, R. Prout, N. Rae, H. Reschreiter, Tim Reynolds, Neil Richardson, M. Roberts, D. Roberts, A. Rose, G. Rousseau, Brendan J. Ryan, Taranprit Saluja, A. Shah, Prad Shanmuga, Anil Sharma, A. Shawcross, J. Sizer, M. Shankar-Hari, Richard Smith, C. Snelson, N. Spittle, N. Staines, T. Stambach, R. Stewart, P. Subudhi, T. Szakmany, K. Tatham, Jordan Thomas, C. Thompson, Robert Thompson, A. Tridente, Darell Tupper-Carey, M. Twagira, A. Ustianowski, N. Vallotton, L. Vincent-Smith, S. Visuvanathan, A. Vuylsteke, S. Waddy, R. Wake, A. Walden, I. Welters, T. Whitehouse, P. Whittaker, A. Whittington, M. Wijesinghe, Martin Williams, Lawrence Wilson, Sarah Wilson, S. Winchester, M. Wiselka, A. Wolverson, D. Wooton, A. Workman, B. Yates, Peter Young   +397 more
semanticscholar   +1 more source

Long-Term Safety and Efficacy of Tocilizumab in Early Systemic Sclerosis-Interstitial Lung Disease: Open Label Extension of a Phase 3 Randomized Controlled Trial.

American Journal of Respiratory and Critical Care Medicine, 2021
RATIONALE Tocilizumab, an anti-interleukin-6 receptor antibody, had no statistically significant effect on skin sclerosis but preserved lung function over 48 weeks in patients with early systemic sclerosis-associated interstitial lung disease in a phase ...
D. Khanna, Celia J. F. Lin, D. Furst, Bridget Wagner, M. Zucchetto, G. Raghu, F. Martinez, J. Goldin, J. Siegel, C. Denton   +9 more
semanticscholar   +1 more source

Fibro-CoSANet: Pulmonary Fibrosis Prognosis Prediction using a Convolutional Self Attention Network [PDF]

, 2021
Idiopathic pulmonary fibrosis (IPF) is a restrictive interstitial lung disease that causes lung function decline by lung tissue scarring. Although lung function decline is assessed by the forced vital capacity (FVC), determining the accurate progression of IPF remains a challenge. To address this challenge, we proposed Fibro-CoSANet, a novel end-to-end
arxiv   +1 more source

Nintedanib for Systemic Sclerosis-Associated Interstitial Lung Disease.

New England Journal of Medicine, 2019
BACKGROUND Interstitial lung disease (ILD) is a common manifestation of systemic sclerosis and a leading cause of systemic sclerosis-related death. Nintedanib, a tyrosine kinase inhibitor, has been shown to have antifibrotic and antiinflammatory effects ...
O. Distler, K. Highland, M. Gahlemann, A. Azuma, A. Fischer, M. Mayes, G. Raghu, W. Sauter, M. Girard, M. Alves, E. Clerisme-Beaty, S. Stowasser, K. Tetzlaff, M. Kuwana, T. Maher   +14 more
semanticscholar   +1 more source

Progressive interstitial lung disease in patients with systemic sclerosis-associated interstitial lung disease in the EUSTAR database

Annals of the Rheumatic Diseases, 2020
Objectives To identify overall disease course, progression patterns and risk factors predictive for progressive interstitial lung disease (ILD) in patients with systemic sclerosis-associated ILD (SSc-ILD), using data from the European Scleroderma Trials ...
A. Hoffmann-Vold, Y. Allanore, M. Alves, C. Brunborg, P. Airó, L. Ananieva, L. Czirják, S. Guiducci, E. Hachulla, Mengtao Li, C. Mihai, G. Riemekasten, P. Sfikakis, O. Kowal-Bielecka, A. Riccardi, O. Distler   +15 more
semanticscholar   +1 more source

Comorbidities in interstitial lung diseases

European Respiratory Review, 2017
Fibrosing lung disorders include a large number of diseases with diverse behaviour. Patients can die because of the progression of their illness, remain stable or even improve after appropriate treatment has been instituted.
George A. Margaritopoulos, Katerina M. Antoniou, Athol U. Wells   +2 more
doaj   +1 more source

Idiopathic pulmonary fibrosis cluster analysis highlights diagnostic delay and cardiovascular comorbidity association with outcome

ERJ Open Research, 2021
Introduction Idiopathic pulmonary fibrosis (IPF) prognosis is heterogeneous despite antifibrotic treatment. Cluster analysis has proven to be a useful tool in identifying interstitial lung disease phenotypes, which has yet to be performed in IPF. The aim
Jaume Bordas-Martínez, Ricard Gavaldà, Jessica G. Shull, Vanesa Vicens-Zygmunt, Lurdes Planas-Cerezales, Guadalupe Bermudo-Peloche, Salud Santos, Neus Salord, Carmen Monasterio, Maria Molina-Molina, Guillermo Suarez-Cuartin   +10 more
doaj   +1 more source

In-hospital mortality following surgical lung biopsy for interstitial lung disease in the USA: 2000-2011 [PDF]

, 2016
Rationale: Surgical lung biopsy can help to determine a specific diagnosis in interstitial lung disease, but has associated risks. Most currently available mortality data are derived from case series and may not be generalizable to broader populations.
Fogarty, Andrew W., Hubbard, Richard B., Hutchinson, John P., McKeever, Tricia M.   +3 more
core   +1 more source

Methotrexate and rheumatoid arthritis associated interstitial lung disease

European Respiratory Journal, 2020
Question addressed by the study Methotrexate (MTX) is a key anchor drug for rheumatoid arthritis (RA) management. Fibrotic interstitial lung disease (ILD) is a common complication of RA.
P. Juge, Joyce S. Lee, J. Lau, L. Kawano-Dourado, J. Serrano, M. Sebastiani, G. Koduri, E. Matteson, K. Bonfiglioli, M. Sawamura, R. Kairalla, L. Cavagna, E. B. Cassione, A. Manfredi, M. Mejía, P. Rodríguez-Henríquez, M. González-Pérez, R. Falfán-Valencia, I. Buendía-Roldán, G. Pérez-Rubio, E. Ebstein, S. Gazal, S. Gazal, R. Borie, S. Ottaviani, C. Kannengiesser, B. Wallaert, Y. Uzunhan, H. Nunes, D. Valeyre, N. Saidenberg-Kermanac’h, M. Boissier, L. Wémeau-Stervinou, R. Flipo, S. Marchand-Adam, P. Richette, P. Richette, Y. Allanore, Y. Allanore, C. Dromer, M. Truchetet, C. Richez, T. Schaeverbeke, H. Lioté, G. Thabut, K. Deane, J. Solomon, T. Doyle, J. Ryu, I. Rosas, V. Holers, C. Boileau, M. Debray, R. Porcher, D. Schwartz, R. Vassallo, B. Crestani, P. Dieudé   +57 more
semanticscholar   +1 more source

Personalised medicine in interstitial lung diseases

European Respiratory Review, 2018
Interstitial lung diseases in general, and idiopathic pulmonary fibrosis in particular, are complex disorders with multiple pathogenetic pathways, various disease behaviour profiles and different responses to treatment, all facets that make personalised ...
Maria A. Kokosi, George A. Margaritopoulos, Athol U. Wells   +2 more
doaj   +1 more source