Results 31 to 40 of about 162,220 (306)

Overnight desaturation in interstitial lung diseases: links to pulmonary vasculopathy and mortality

ERJ Open Research
Background Overnight desaturation predicts poor prognosis across interstitial lung diseases (ILDs). The aim of the present study was to investigate whether nocturnal desaturation is associated with pulmonary vasculopathy and mortality.
George A. Margaritopoulos, Athanasia Proklou, Athina Trachalaki, Diana Badenes Bonet, Maria Kokosi, Vasilis Kouranos, Felix Chua, Peter George, Elisabetta A. Renzoni, Anand Devaraj, Sujal Desai, Andrew G. Nicholson, Katerina M. Antoniou, Athol U. Wells   +13 more
doaj   +1 more source

Systematic review of drug effects in humans and models with surfactant-processing disease

European Respiratory Review, 2018
Fibrotic interstitial pneumonias are a group of rare diseases characterised by distortion of lung interstitium. Patients with mutations in surfactant-processing genes, such as surfactant protein C (SFTPC), surfactant protein A1 and A2 (SFTPA1 and A2 ...
Dymph Klay, Thijs W. Hoffman, Ankie M. Harmsze, Jan C. Grutters, Coline H.M. van Moorsel   +4 more
doaj   +1 more source

A Retrospective Analysis of 2-Year Follow-Up of Patients with Incidental Findings of Sarcoidosis

Diagnostics
Introduction: Sarcoidosis is a multi-system granulomatous disease most commonly involving the lungs. It may be incidentally diagnosed during imaging studies for other conditions or non-specific symptoms.
Oluwabukola Thomas-Orogan, Shaney L. Barratt, Muhammad Zafran, Apollo Kwok, Anneliese Simons, Eoin P. Judge, Matthew Wells, Richard Daly, Charles Sharp, Abiramy Jeyabalan, Martin Plummeridge, Ladli Chandratreya, Lisa G. Spencer, Andrew R. L. Medford, Huzaifa I. Adamali   +14 more
doaj   +1 more source

An Infant with Interstitial Lung Disease [PDF]

Indian Pediatrics, 2019
Interstitial lung disease in infants, unlike older children and adults, has diverse etiology, including infective, metabolic, autoimmune, genetic, malignant and idiopathic causes. Clinical recognition of the interstitial pattern of lung involvement is important as the etiology and management is entirely different from that of recurrent or chronic lung ...
Pandiarajan Vignesh, Pankaj C Vaidya, Kushaljit Singh Sodhi, Meenu Singh, Uma Nahar   +4 more
openaire   +3 more sources

Interstitial lung disease and diabetes

World Journal of Diabetes, 2020
Diabetes mellitus (DM) is a chronic metabolic disease and its prevalence has been steadily increasing all over the world. DM and its associated micro and macrovascular complications result in significant morbidity and mortality. The microvascular complications are usually manifested as retinopathy, neuropathy, nephropathy and macrovascular ...
Salim Surani, Kulothungan Gunasekaran, Venkat Rajasurya   +2 more
openaire   +3 more sources

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Matrix: a complex amalgam of structures and functions in tumor microenvironment

FEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis, Evgenia Tsoukala, Theodora D. Sarantopoulou, Maria‐Elpida Christopoulou   +3 more
wiley   +1 more source

Present and future perspectives in early diagnosis and monitoring for progressive fibrosing interstitial lung diseases

Frontiers in Medicine, 2023
Progressive fibrosing interstitial lung diseases (PF-ILDs) represent a group of conditions of both known and unknown origin which continue to worsen despite standard treatments, leading to respiratory failure and early mortality.
Stefan Cristian Stanel, Stefan Cristian Stanel, Pilar Rivera-Ortega   +2 more
doaj   +1 more source

LOXHD1 and RHOB Expression by Monocytes Predicts Progressive Systemic Sclerosis associated Interstitial Lung Disease

Arthritis Care &Research, Accepted Article.
Objective A leading cause of death among scleroderma (SSc) patients, interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M Padilla, Robert Lafyatis, Kevin F Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J Kass   +13 more
wiley   +1 more source

Ambulatory oxygen in fibrotic lung disease (AmbOx): study protocol for a randomised controlled trial

Trials, 2017
Background Fibrotic interstitial lung diseases (ILDs) are chronic and often progressive conditions resulting in substantial morbidity and mortality. Shortness of breath, a symptom often linked to oxygen desaturation on exertion, is tightly linked to ...
Dina Visca, Vicky Tsipouri, Letizia Mori, Ashi Firouzi, Sharon Fleming, Morag Farquhar, Elizabeth Leung, Toby M. Maher, Paul Cullinan, Nick Hopkinson, Athol U. Wells, Winston Banya, Jennifer A. Whitty, Huzaifa Adamali, Lisa G. Spencer, Piersante Sestini, Elisabetta A. Renzoni   +16 more
doaj   +1 more source