Results 21 to 30 of about 172,093 (166)

Immune mechanisms in fibrotic pulmonary sarcoidosis

open access: yesEuropean Respiratory Review, 2022
Sarcoidosis is an immune-mediated disorder. Its immunopathology has been steadily mapped out over the past few decades. Despite this, the underpinning mechanisms for progressive fibrotic sarcoidosis is an almost uncharted area.
Praveen Weeratunga   +2 more
doaj   +1 more source

Overnight desaturation in interstitial lung diseases: links to pulmonary vasculopathy and mortality

open access: yesERJ Open Research
Background Overnight desaturation predicts poor prognosis across interstitial lung diseases (ILDs). The aim of the present study was to investigate whether nocturnal desaturation is associated with pulmonary vasculopathy and mortality.
George A. Margaritopoulos   +13 more
doaj   +1 more source

Genetic Interstitial Lung Disease [PDF]

open access: yesClinics in Chest Medicine, 2012
The interstitial lung diseases (ILDs), or diffuse parenchymal lung diseases, are a heterogeneous collection of more than 100 different pulmonary disorders that affect the tissue and spaces surrounding the alveoli. Patients affected by ILD usually present with shortness of breath or cough; for many, there is evidence of pulmonary restriction, decreased ...
Megan Stuebner, Devine   +1 more
openaire   +2 more sources

Patient perspectives on home-spirometry in interstitial lung disease: a qualitative co-designed study

open access: yesBMJ Open Respiratory Research, 2023
Background Opportunities for home-monitoring are increasing exponentially. Home- spirometry is reproducible and reliable in interstitial lung disease (ILD), yet patients’ experiences are not reported.
Sarah Lines   +19 more
doaj   +1 more source

Systematic review of drug effects in humans and models with surfactant-processing disease

open access: yesEuropean Respiratory Review, 2018
Fibrotic interstitial pneumonias are a group of rare diseases characterised by distortion of lung interstitium. Patients with mutations in surfactant-processing genes, such as surfactant protein C (SFTPC), surfactant protein A1 and A2 (SFTPA1 and A2 ...
Dymph Klay   +4 more
doaj   +1 more source

Recent advances in the treatment of systemic sclerosis associated interstitial lung disease

open access: yesFrontiers in Medicine, 2023
Connective tissue diseases (CTDs) are a heterogenous group of systemic inflammatory disorders. The development of connective tissue disease-associated interstitial lung disease (CTD-ILD) is a key complication associated with significant morbidity and ...
Antoniya Kamenova   +2 more
doaj   +1 more source

Evolving Concepts in Progressive Pulmonary Fibrosis: A Clinical Update

open access: yesJournal of Respiration
Progressive pulmonary fibrosis (PPF) is a clinical syndrome associated with worsening quality of life and increased mortality among patients with various interstitial lung diseases.
María Belén Noboa-Sevilla   +8 more
doaj   +1 more source

A Retrospective Analysis of 2-Year Follow-Up of Patients with Incidental Findings of Sarcoidosis

open access: yesDiagnostics
Introduction: Sarcoidosis is a multi-system granulomatous disease most commonly involving the lungs. It may be incidentally diagnosed during imaging studies for other conditions or non-specific symptoms.
Oluwabukola Thomas-Orogan   +14 more
doaj   +1 more source

Pleuroparenchymal sarcoidosis - A recognised but rare manifestation of disease

open access: yesRespiratory Medicine Case Reports, 2018
Pleural involvement is rare in sarcoidosis. The presence of a large symptomatic effusion in a patient with sarcoidosis should therefore prompt further investigation for an alternate aetiology.
S. Walker   +4 more
doaj   +1 more source

Smoking and interstitial lung diseases

open access: yesEuropean Respiratory Review, 2015
For many years has been well known that smoking could cause lung damage. Chronic obstructive pulmonary disease and lung cancer have been the two most common smoking-related lung diseases.
George A. Margaritopoulos   +4 more
doaj   +1 more source

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