Results 21 to 30 of about 182,063 (264)
Overnight desaturation in interstitial lung diseases: links to pulmonary vasculopathy and mortality
ERJ Open ResearchBackground Overnight desaturation predicts poor prognosis across interstitial lung diseases (ILDs). The aim of the present study was to investigate whether nocturnal desaturation is associated with pulmonary vasculopathy and mortality.
George A. Margaritopoulos +13 more
doaj +1 more source
Prognostic factors in chronic hypersensitivity pneumonitis
European Respiratory Review, 2020 Hypersensitivity pneumonitis (HP) is an immunologically mediated lung disease resulting from exposure to inhaled environmental antigens. Prognosis is variable, with a subset of patients developing progressive fibrosis leading to respiratory failure and ...
Andrew W. Creamer, Shaney L. Barratt
doaj +1 more source
Immune mechanisms in fibrotic pulmonary sarcoidosis
European Respiratory Review, 2022 Sarcoidosis is an immune-mediated disorder. Its immunopathology has been steadily mapped out over the past few decades. Despite this, the underpinning mechanisms for progressive fibrotic sarcoidosis is an almost uncharted area.
Praveen Weeratunga +2 more
doaj +1 more source
BMJ Open Respiratory Research, 2023 Background Opportunities for home-monitoring are increasing exponentially. Home- spirometry is reproducible and reliable in interstitial lung disease (ILD), yet patients’ experiences are not reported.
Sarah Lines +19 more
doaj +1 more source
Interstitial lung diseases in children
La Presse Médicale, 2020 Interstitial lung disease (ILD) in children (chILD) is a heterogeneous group of rare respiratory disorders that are mostly chronic and associated with high morbidity and mortality. The pathogenesis of the various chILD is complex and the diseases share common features of inflammatory and fibrotic changes of the lung parenchyma that impair gas exchanges.
Nadia, Nathan +4 more
openaire +3 more sources
Systematic review of drug effects in humans and models with surfactant-processing disease
European Respiratory Review, 2018 Fibrotic interstitial pneumonias are a group of rare diseases characterised by distortion of lung interstitium. Patients with mutations in surfactant-processing genes, such as surfactant protein C (SFTPC), surfactant protein A1 and A2 (SFTPA1 and A2 ...
Dymph Klay +4 more
doaj +1 more source
Evolving Concepts in Progressive Pulmonary Fibrosis: A Clinical Update
Journal of RespirationProgressive pulmonary fibrosis (PPF) is a clinical syndrome associated with worsening quality of life and increased mortality among patients with various interstitial lung diseases.
María Belén Noboa-Sevilla +8 more
doaj +1 more source
Recent advances in the treatment of systemic sclerosis associated interstitial lung disease
Frontiers in Medicine, 2023 Connective tissue diseases (CTDs) are a heterogenous group of systemic inflammatory disorders. The development of connective tissue disease-associated interstitial lung disease (CTD-ILD) is a key complication associated with significant morbidity and ...
Antoniya Kamenova +2 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
A Retrospective Analysis of 2-Year Follow-Up of Patients with Incidental Findings of Sarcoidosis
DiagnosticsIntroduction: Sarcoidosis is a multi-system granulomatous disease most commonly involving the lungs. It may be incidentally diagnosed during imaging studies for other conditions or non-specific symptoms.
Oluwabukola Thomas-Orogan +14 more
doaj +1 more source