Results 31 to 40 of about 5,706,732 (263)

Prognostic factors in chronic hypersensitivity pneumonitis

European Respiratory Review, 2020
Hypersensitivity pneumonitis (HP) is an immunologically mediated lung disease resulting from exposure to inhaled environmental antigens. Prognosis is variable, with a subset of patients developing progressive fibrosis leading to respiratory failure and ...
Andrew W. Creamer, Shaney L. Barratt
doaj   +1 more source

Immune mechanisms in fibrotic pulmonary sarcoidosis

European Respiratory Review, 2022
Sarcoidosis is an immune-mediated disorder. Its immunopathology has been steadily mapped out over the past few decades. Despite this, the underpinning mechanisms for progressive fibrotic sarcoidosis is an almost uncharted area.
Praveen Weeratunga, David R. Moller, Ling-Pei Ho   +2 more
doaj   +1 more source

Overnight desaturation in interstitial lung diseases: links to pulmonary vasculopathy and mortality

ERJ Open Research
Background Overnight desaturation predicts poor prognosis across interstitial lung diseases (ILDs). The aim of the present study was to investigate whether nocturnal desaturation is associated with pulmonary vasculopathy and mortality.
George A. Margaritopoulos, Athanasia Proklou, Athina Trachalaki, Diana Badenes Bonet, Maria Kokosi, Vasilis Kouranos, Felix Chua, Peter George, Elisabetta A. Renzoni, Anand Devaraj, Sujal Desai, Andrew G. Nicholson, Katerina M. Antoniou, Athol U. Wells   +13 more
doaj   +1 more source

Patient perspectives on home-spirometry in interstitial lung disease: a qualitative co-designed study

BMJ Open Respiratory Research, 2023
Background Opportunities for home-monitoring are increasing exponentially. Home- spirometry is reproducible and reliable in interstitial lung disease (ILD), yet patients’ experiences are not reported.
Sarah Lines, Michael Gibbons, Rebecca Shuttleworth, Anne-Marie Russell, Graham Brown, Anna Duckworth, Alex Berry, Jessica Mandizha, Joseph W Lanario, Ana Paiva, Victoria Elworthy, Veena Muraleedharan, Ana Jorge Da Ponte, Howard Almond, Carole Bond, Maureen Cosby, Joanne Dallas, Marium Naqvi, Adam David Russell, Christopher J Scotton   +19 more
doaj   +1 more source

A fatal case of acute exacerbation of interstitial lung disease in a patient with rheumatoid arthritis during treatment with tocilizumab. [PDF]

, 2012
A 68-year-old man, who was a patient with established rheumatoid arthritis (RA) with RA-associated interstitial lung disease (RA-ILD) and pulmonary emphysema, began taking tocilizumab. Subsequently, he developed dyspnea parallel to improvement of RA.
Kawashiri, Shin-Ya, Eguchi, Katsumi, Ishimatsu, Yuji, Kawakami, Atsushi, Sakamoto, Noriho   +4 more
core   +1 more source

Recent advances in the treatment of systemic sclerosis associated interstitial lung disease

Frontiers in Medicine, 2023
Connective tissue diseases (CTDs) are a heterogenous group of systemic inflammatory disorders. The development of connective tissue disease-associated interstitial lung disease (CTD-ILD) is a key complication associated with significant morbidity and ...
Antoniya Kamenova, Argyris Tzouvelekis, George A. Margaritopoulos   +2 more
doaj   +1 more source

Systematic review of drug effects in humans and models with surfactant-processing disease

European Respiratory Review, 2018
Fibrotic interstitial pneumonias are a group of rare diseases characterised by distortion of lung interstitium. Patients with mutations in surfactant-processing genes, such as surfactant protein C (SFTPC), surfactant protein A1 and A2 (SFTPA1 and A2 ...
Dymph Klay, Thijs W. Hoffman, Ankie M. Harmsze, Jan C. Grutters, Coline H.M. van Moorsel   +4 more
doaj   +1 more source

Evolving Concepts in Progressive Pulmonary Fibrosis: A Clinical Update

Journal of Respiration
Progressive pulmonary fibrosis (PPF) is a clinical syndrome associated with worsening quality of life and increased mortality among patients with various interstitial lung diseases.
María Belén Noboa-Sevilla, Fernanda Hernández-González, Sandra Cuerpo-Cardeñosa, Xavier Alsina-Restoy, Nancy Pérez-Rodas, Alejandro Frino-García, Miguel Alonso-Villares, Elvis Matheus-Ramírez, Jacobo Sellarés   +8 more
doaj   +1 more source

Interstitial lung disease in Malta [PDF]

, 2012
Aim: To establish the prevalence, management and response to treatment of interstitial lung disease (ILD) in Malta. Methodology: The personal files of 102 living and 26 deceased patients with ILD under the care of 4 respiratory physicians were reviewed ...
Fenech, Manwel, Gouder, Caroline, Montefort, Stephen   +2 more
core  

Genetics of Interstitial Lung Disease: (Night Flight)

, 2015
Interstitial lung disease (ILD) is a chronic, progressive fibrotic lung disease with a dismal prognosis. ILD of unknown etiology is referred to as idiopathic interstitial pneumonia (IIP), which is sporadic in the majority of cases.
Kota Shimada, Shigeto Tohma, Naoyuki Tsuchiya, Hiroshi Furukawa, Shomi Oka   +4 more
core   +1 more source