Results 81 to 90 of about 774,384 (405)

Heterogeneity of Rheumatoid Arthritis–Associated Interstitial Lung Disease by Longitudinal Forced Vital Capacity Trajectory and Associations With Disease Outcomes

Arthritis Care &Research, EarlyView.
Objective We aimed to identify unique disease trajectories within rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) based on longitudinal forced vital capacity (FVC) values and their associated clinical outcomes. Methods We performed a cohort study of RA‐ILD within the Veterans Health Administration from 1999 to 2021.
Bryant R. England, Yangyuna Yang, Punyasha Roul, Tate M. Johnson, Scott M. Matson, Grant W. Cannon, Brian C. Sauer, Jeffrey R. Curtis, Joshua F. Baker, Ted R. Mikuls   +9 more
wiley   +1 more source

Ambulatory oxygen in fibrotic lung disease (AmbOx): study protocol for a randomised controlled trial

Trials, 2017
Background Fibrotic interstitial lung diseases (ILDs) are chronic and often progressive conditions resulting in substantial morbidity and mortality. Shortness of breath, a symptom often linked to oxygen desaturation on exertion, is tightly linked to ...
Dina Visca, Vicky Tsipouri, Letizia Mori, Ashi Firouzi, Sharon Fleming, Morag Farquhar, Elizabeth Leung, Toby M. Maher, Paul Cullinan, Nick Hopkinson, Athol U. Wells, Winston Banya, Jennifer A. Whitty, Huzaifa Adamali, Lisa G. Spencer, Piersante Sestini, Elisabetta A. Renzoni   +16 more
doaj   +1 more source

Present and future perspectives in early diagnosis and monitoring for progressive fibrosing interstitial lung diseases

Frontiers in Medicine, 2023
Progressive fibrosing interstitial lung diseases (PF-ILDs) represent a group of conditions of both known and unknown origin which continue to worsen despite standard treatments, leading to respiratory failure and early mortality.
Stefan Cristian Stanel, Stefan Cristian Stanel, Pilar Rivera-Ortega   +2 more
doaj   +1 more source

Sequencing of idiopathic pulmonary fibrosis-related genes reveals independent single gene associations [PDF]

, 2014
BACKGROUND: Previous studies investigating a genetic basis for idiopathic pulmonary fibrosis (IPF) have focused on resequencing single genes in IPF kindreds or cohorts to determine the genetic contributions to IPF.
Coghlan, Meghan A, Cole, F. Sessions, Hamvas, Aaron, Huang, Howard J, Mitra, Robi D, Russell, Tonya D, Shifren, Adrian, Wegner, Daniel J, Zhang, Qunyuan   +8 more
core   +3 more sources

Rethinking Strategies for a Pharmaceutical Approach to Pain Related to Connective Tissue–Related Raynaud Phenomenon in the United States

Arthritis Care &Research, EarlyView.
Objective There are no US Food and Drug Administration–approved therapies for Raynaud phenomenon (RP) in the United States. Clinical trials have been challenged by study design. Important advances in RP patient‐reported outcome measures and mechanistic quantification allow RP‐related pain characterization.
Tracy M. Frech, Charles G. Frech, W. David Merryman, Andrew Sternlicht, Justin Baba   +4 more
wiley   +1 more source

Prediction of progressive pulmonary fibrosis in patients with anti-synthetase syndrome-associated interstitial lung disease [PDF]

, 2023
Hongyan Fu, Ziyao Zheng, Zhenping Zhang, Yanjuan Yang, Jieda Cui, Zhaojun Wang, Jing Xue, Shuhong Chi, Mengshu Cao, Juan Chen   +9 more
openalex   +1 more source

Mechanisms of progressive fibrosis in connective tissue disease (CTD)-associated interstitial lung diseases (ILDs)

Annals of the Rheumatic Diseases, 2020
Interstitial lung diseases (ILDs), which can arise from a broad spectrum of distinct aetiologies, can manifest as a pulmonary complication of an underlying autoimmune and connective tissue disease (CTD-ILD), such as rheumatoid arthritis-ILD and systemic ...
P. Spagnolo, O. Distler, C. Ryerson, A. Tzouvelekis, Joyce S. Lee, F. Bonella, Demosthenes Bouros, A. Hoffmann-Vold, B. Crestani, E. Matteson   +9 more
semanticscholar   +1 more source

99mTc-MIBI Lung Scintigraphy in the Assessment of Pulmonary Involvement in Interstitial Lung Disease and Its Comparison With Pulmonary Function Tests and High-Resolution Computed Tomography: A Preliminary Study [PDF]

, 2015
The differentiation of active inflammatory processes from an inactive form of the disease is of great value in the management of interstitial lung disease (ILD).
Assadi, M., Bahtouee, M., Eftekhari, M., Javadi, H., Nabipour, I., Raeisi, A., Saberifard, J.   +6 more
core   +2 more sources

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

Arthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg, Izzy Hartel, Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte‐García, Victoria P. Werth, Brad Rovin, Reem A. Mustafa, Amy S. Turner, Bené Williams, Brian L. Ung, Hiya Bhavsar, Monique C. Gore‐Massy, Nahirannette Pulido, Natacha Guerrero, Natalie M. Smith, Wambui Machua, Linda T. Hiraki, Mary Beth Son   +20 more
wiley   +1 more source

Multi-center evaluation of baseline neutrophil-to-lymphocyte (NLR) ratio as an independent predictor of mortality and clinical risk stratifier in idiopathic pulmonary fibrosisResearch in context

EClinicalMedicine, 2023
Summary: Background: Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal disorder with a variable disease trajectory. The aim of this study was to assess the potential of neutrophil-to-lymphocyte ratio (NLR) to predict outcomes in IPF.
Theresia A. Mikolasch, Peter M. George, Jagdeep Sahota, Thomas Nancarrow, Shaney L. Barratt, Felix A. Woodhead, Vasilis Kouranos, Victoria S.A. Cope, Andrew W. Creamer, Silan Fidan, Balaji Ganeshan, Luke Hoy, John A. Mackintosh, Robert Shortman, Anna Duckworth, Janet Fallon, Helen Garthwaite, Melissa Heightman, Huzaifa I. Adamali, Sarah Lines, Thida Win, Rebecca Wollerton, Elisabetta A. Renzoni, Matthew Steward, Athol U. Wells, Michael Gibbons, Ashley M. Groves, Bibek Gooptu, Chris J. Scotton, Joanna C. Porter   +29 more
doaj   +1 more source