Results 101 to 110 of about 142,066 (310)

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Pulmonary lymphangiomatosis: insights into an ultra-rare disease

Respiratory Research
Background Pulmonary lymphangiomatosis (PL) is an ultrarare disease characterized by diffuse infiltration of the lung, pleura and/or mediastinum by abnormal lymphatic proliferation. Consented diagnostic or treatment approaches are not established.
M. Polke, N. Polke, S. Piel, E. Brunnemer, J. Wälscher, K. Buschulte, A. Warth, C. P. Heussel, M. Eichinger, L. Frankenstein, M. Eichhorn, S. Miliauskas, F. J. F. Herth, M. Kreuter   +13 more
doaj   +1 more source

Smoking-related interstitial lung disease

, 2011
Cigarette smoking has a clear epidemiological association with lung diseases, characterised by chronic inflammation of both the bronchiolar and the interstitial lung compartments.
P. Spagnolo, CERRI, Stefania, SPAGNOLO, Paolo, RICHELDI, Luca, F. Luppi, S. Cerri, L. Richeldi   +6 more
core   +1 more source

Interstitial lung disease in the course of systemic connective tissue diseases: A common problem for rheumatologists and pulmonologists

, 2022
Interstitial lung disease is a common and dangerous complication of many rheumatic diseases. Progress over the last several years has increased diagnostic capabilities, led to emergence of new therapeutic options and, above all, resulted in deeper ...
Szymanowska-Narloch, Amelia; Department of Allergology, University Clinical Centre in Gdańsk, Poland, Zdrojewski, Zbigniew; Department of Internal Medicine, Connective Tissue Diseases & Geriatrics, Medical University of Gdańsk, Poland, Gogulska, Zuzanna; Department of Internal Medicine, Connective Tissue Diseases & Geriatrics, Medical University of Gdańsk, Poland, Smoleńska, Żaneta; Department of Internal Medicine, Connective Tissue Diseases & Geriatrics, Medical University of Gdańsk, Poland   +3 more
core   +1 more source

Interstitial Lung Disease

JAMA
ImportanceInterstitial lung disease (ILD) consists of a group of pulmonary disorders characterized by inflammation and/or fibrosis of the lung parenchyma associated with progressive dyspnea that frequently results in end-stage respiratory failure. In the US, ILD affects approximately 650 000 people and causes approximately 25 000 to 30 000 deaths per ...
openaire   +3 more sources

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source

Microgel‐Based 3D Bioprinting: A Convergent Strategy Integrating Material Design, Jamming Dynamics, and Biological Function

Advanced Healthcare Materials, EarlyView.
Microgel‐based 3D printed constructs represent a compelling and versatile innovation for engineering architecturally complex, dynamically remodelable, and biocompatible structures with high structural fidelity and bioactivity. By integrating material design, biofabrication, and biological function, these systems enable the development of adaptive ...
Elena Ghighină, Andreea Ioana Dinu, Jana Ghițman   +2 more
wiley   +1 more source

Local lung responses following endobronchial elastase and lipopolysaccharide instillation in sheep

, 2006
Chronic lipopolysaccharide (LPS) exposure may contribute to the pathogenesis of a number of lung diseases including COPD and emphysema. We sought to develop a large-animal model of emphysema using repeated LPS administration into sheep lung segments.
Blundell, Richard, Rhind, Susan; id_orcid, McLean, Nicola, Rhind, Susan, Milne, Elspeth, Woodall, Chris, Collie, D David S, Baker, Alison, Sallenave, Jean-Michel   +8 more
core   +1 more source