Development of an efficient mice model of cancer‐associated cardiac cachexia
Animal Models and Experimental Medicine, EarlyView.This work establishes a preclinical framework for targeting ubiquitin pathways to mitigate the morbidity of cancer‐related cardiopathy. Our integrated approach delineates a hierarchical progression from subcellular dysfunction to macroscopic cardiac deterioration. These findings mechanistically link tumor‐induced cachexia to cardiac dysfunction through
Shijie Xiong +9 more
wiley +1 more source
Family history of pulmonary fibrosis impacts prognosis in patients with sarcoidosis
ERJ Open ResearchThomas Planté-Bordeneuve +6 more
doaj +1 more source
Risk Factors for Radiation Pneumonitis in Lung Cancer Patients with Subclinical Interstitial Lung Disease after Thoracic Radiation Therapy [PDF]
, 2021 Fangjuan Li +4 more
openalex +1 more source
New approaches to treating chronic obstructive pulmonary disease with Colla corii asini
Animal Models and Experimental Medicine, EarlyView.Colla corii asini improves chronic obstructive pulmonary disease (COPD) treatment through anti‐inflammatory, antioxidant, immune‐modulatory, and lung‐nourishing effects, addressing current therapeutic challenges via multitarget mechanisms. Abstract Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability ...
Wenchao Zhang +5 more
wiley +1 more source
Clinical and laboratory features of fatal rapidly progressive interstitial lung disease associated with juvenile dermatomyositis [PDF]
, 2014 Norihiro Kobayashi +20 more
openalex +1 more source
The use of transgenic animals for xenotransplantation: An update
Animal Models and Experimental Medicine, EarlyView.One way to produce genetically modified pigs is to use somatic cell nuclear transfer (SCNT). This procedure involves removing the metaphase plate from a mature oocyte using micromanipulation and then transferring the modified nucleus from the donor somatic cell to the oocyte.
Julia Motławska +3 more
wiley +1 more source
Altered monocyte and fibrocyte phenotype and function in scleroderma interstitial lung disease: reversal by caveolin-1 scaffolding domain peptide [PDF]
, 2011 Elena Tourkina +10 more
openalex +1 more source
Advanced NanoBiomed Research, EarlyView.Ultrasound contrast agents, including microbubbles and nanobubbles, transform imaging and targeted therapy through precise engineering of size, shell composition, and surface properties. This review explores how these innovations enable tissue‐specific delivery, enhance therapeutic efficacy, and extend applications from vascular imaging to tumor ...
Ashkan Seza +2 more
wiley +1 more source
Imatinib-induced irreversible interstitial lung disease
, 2019 Ping Zhang +4 more
openalex +1 more source