e-Lung computed tomography biomarkers are associated with outcomes in fibrotic interstitial lung diseases. [PDF]
Abbasi Dezfouli K +18 more
europepmc +1 more source
Refining a preclinical model of viral myocarditis in accordance with biotech standards
This study aimed to refine a murine model of Coxsackievirus B3‐induced myocarditis by integrating dietary and imaging innovations to improve animal welfare, data quality, and clinical applicability. The refined diet significantly reduced animal health burden, reduced weight loss, and stabilized blood glucose during development of cardiac inflammation ...
Jonas Stewen +9 more
wiley +1 more source
The Genetic Landscape of Fibrotic Interstitial Lung Diseases: Clinical Implications and Diagnostic Challenges in Familial Pulmonary Fibrosis. [PDF]
Tirelli C +9 more
europepmc +1 more source
Nanofabricated Biomaterials Model Tumor Extracellular Matrix Topography
The unique structure and composition of the tumor microenvironment and its associated extracellular matrix (ECM) exert profound effects on cancer cell behavior that are difficult to model in vitro. This perspective discusses the utility of nanofabricated biosubstrates, such as the novel collagen‐coated nanogrooved array, for recapitulating the ...
Vic Zamloot, JinSeok Park
wiley +1 more source
Association of CD32-131H>R Polymorphism with End-Stage Chronic Obstructive Pulmonary Disease and Interstitial Lung Diseases. [PDF]
Berger SM +6 more
europepmc +1 more source
Three‐dimensional geometric morphometric analysis of diaphragmatic dome motion in COPD patients
Abstract Diaphragmatic dysfunction is a hallmark of chronic obstructive pulmonary disease (COPD), especially in emphysema, where hyperinflation alters diaphragm geometry and impairs inspiratory mechanics. However, quantitative three‐dimensional (3D) assessments of diaphragmatic dome shape and motion across COPD phenotypes are limited.
José M. López‐Rey +5 more
wiley +1 more source
Non-pharmacological Management of Fibrosing Interstitial Lung Diseases. [PDF]
Kaenmuang P, Yip WH, Kahai R, Fabbri L.
europepmc +1 more source
Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm +2 more
wiley +1 more source
Association of bronchoalveolar lavage cellular analysis and radiological findings in fibrotic interstitial lung diseases. [PDF]
Kaenmuang P +22 more
europepmc +1 more source
Interstitial lung diseases are a group of diffuse parenchymal lung disorders associated with substantial morbidity and mortality. Knowledge achieved in recent years has resulted in the publication of the new classification of idiopathic interstitial ...
oʻgʻli, N. A. (Najmiddinov) +2 more
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