Results 151 to 160 of about 654,309 (397)

Smoking Promotes AT2 Cell Senescence and Exacerbates Pulmonary Fibrosis by Downregulating POT1 via Integratively Inducing CpG Methylation and MECP2‐Mediated FOXP2 Transcriptional Binding Inhibition

Aging Cell, EarlyView.
Smoking is one of the major causes of pulmonary fibrosis (PF), and treatment options for PF are limited. We show that POT1 is decreased in PF patients and mice, especially in smoke exposure, and investigate its contributions to PF progression from protecting AT2 cell senescence to fibrosis. AAV9‐mediated restoration of POT1 prevents PF.
Mengkun Shi, Wei Wang, Posum Wan, Jialun Shi, Huixia Cui, Zhonghan Sun, Xiaofeng Chen, Jingyu Chen, Jiucun Wang, Xiangguang Shi   +9 more
wiley   +1 more source

Desquamative interstitial pneumonia associated with chrysotile asbestos fibres. [PDF]

, 1991
J A Freed, Albert Miller, Ronald E. Gordon, Alf Fischbein, Jerome Kleinerman, Arthur M. Langer   +5 more
openalex   +1 more source

Myeloid cAMP Reduction Shifts Rhinovirus‐Induced Airway Inflammation From Neutrophilic to Eosinophilic by Suppressing M1‐Interstitial Macrophages

Allergy, EarlyView.
ABSTRACT Background Asthma exacerbations caused by human rhinovirus (hRV) infection are characterized by airway neutrophilia and reduced corticosteroid response, leading to significant healthcare costs and lung function impairment. The Gαs subunit of the trimeric G protein regulates immunopathological conditions by modulating cAMP levels.
Seong Ok Park, Erdenebileg Uyangaa, Hyo Jin Kim, Hee Won Byeon, Jin Young Choi, Koanhoi Kim, Jihyung Lee, Samuel Bertin, Eyal Raz, Seong Kug Eo   +9 more
wiley   +1 more source

Limitations to the 6-Minute Walk Test in Dermatomyositis with Interstitial Lung Disease in comparison with Idiopathic Interstitial pneumonia

Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2013
Although the relationship between muscle strength and exercise capacity has been demonstrated in dermatomyositis without lung dysfunction, little is known about the association between exercise capacity and interstitial lung disease in dermatomyositis ...
Fujiko Someya, Naoki Mugii
doaj   +1 more source

Acute Interstitial Pneumonia in Mink Kits Inoculated with Defined Isolates of Aleutian Mink Disease Parvovirus [PDF]

, 1994
Søren Alexandersen, S. Larsen, Bent Aasted, Å. Uttenthal, Marshall E. Bloom, Martin Hansen   +5 more
openalex   +1 more source

Microenvironment‐Driven Mast Cell Plasticity: Insights From Cytokine‐Activated Gene Signatures in Skin and Respiratory Diseases

Allergy, EarlyView.
Primary peripheral blood‐derived human mast cells exposed to IFNγ, IL‐33, IL‐4 + IL‐13, or TGFβ develop distinct transcriptional signatures with unique functional changes including degranulation and cytokine/chemokine release. Machine learning‐defined minimal cytokine‐activated signatures (245 genes) successfully detect cytokine‐primed mast cells in ...
Chiara Tontini, Rajia Bahri, Andrew Higham, Dave Singh, Angela Simpson, Silvia Bulfone‐Paus   +5 more
wiley   +1 more source

Lymphocytic Interstitial Pneumonitis Following Legionnaire's Pneumonia [PDF]

, 1994
Barry S. Dicicco, Glenn Anderson
openalex   +1 more source

Younger Age and Viral Triggers Were Associated With Post‐Infectious Bronchiolitis Obliterans in French Children

Acta Paediatrica, EarlyView.
ABSTRACT Aim Post‐infectious bronchiolitis obliterans (PIBO) is a rare but severe chronic paediatric obstructive lung disease, characterised by the obliteration of small airways following severe lower respiratory tract infections. Epidemiological data in Europe remain limited. Methods This multicentre retrospective study examined the characteristics of
Julie Mazenq, Marine Crebassa, Alice Hadchouel, Souad Ghattas, Philippe Reix, Laurianne Coutier, Christophe Marguet, Nadia Nathan, Lisa Giovannini‐Chami, Caroline Thumerelle, François Galode, Marie‐Catherine Renoux, Léa Roditis, Eglantine Hullo, Pierrick Cros, Laurence Weiss, Sébastien Kiefer, Marie Tochon, Brahim Allali, Katia Bessaci Kabouya, Céline Delestrain, Louisa Goumidi, Hortense Petat, Véronique Houdouin, Jean‐Christophe Dubus   +24 more
wiley   +1 more source

Polyarteritis nodosa and acute interstitial pneumonia. [PDF]

, 1992
Tomoko Matsumoto, Motoi Okada, N Kuwabara, Sakae Homma, Toshio Suzuki, S Kira, T Uekusa, Shinji Saiki   +7 more
openalex   +1 more source

Antimicrobial prescribing guidelines for horses in Australia

Australian Veterinary Journal, EarlyView.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt, K Thomas, S Page, J Norris, G Browning, C El Hage, A Stewart, J Gilkerson, G Muscatello, D Verwilghen, G van Galen, J Bauquier, R Cuming, B Reynolds, C Whittaker, E Wilkes, J Clulow, C Burden, L Begg   +18 more
wiley   +1 more source