Results 301 to 310 of about 672,015 (400)

Fibroblast‐driven MMP‐9/TIMP‐1 imbalance in bronchoalveolar lavage reflects fibrotic progression in interstitial lung disease

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Abstract Background Interstitial lung diseases (ILDs) are characterized by progressive fibrosis, in which extracellular matrix remodelling is regulated by matrix metalloproteinases (MMPs) and their inhibitors (TIMPs). The MMP‐9/TIMP‐1 balance has been implicated in fibrogenesis, but its role in human ILD remains incompletely defined.
Maria Bertolotto, Daniela de Totero, Paolo Giannoni, Emanuela Barisione, Marco Grosso, Ennio Nano, Roberto Fiocca, Simona Pigozzi, Elisabetta Tedone, Luca Valle, Margherita Moriero, Daniela Verzola, Fabrizio Montecucco, Federico Carbone   +13 more
wiley   +1 more source

An Uncommon Case of Non-Specific Interstitial Pneumonia (NSIP) Associated With Idiopathic Hypereosinophilic Syndrome (HES) Reversed by Mepolizumab. [PDF]

Respirol Case Rep
Lipsi R, Coppola A, Carriera L, Moretti R, Dodaj M.   +4 more
europepmc   +1 more source

Safety of Potassium‐Competitive Acid Blockers Compared With Proton Pump Inhibitors in Patients With Gastroesophageal Reflux Disease and Peptic Ulcer Disease: A Systematic Review and Meta‐Analysis

Journal of Gastroenterology and Hepatology, Volume 41, Issue 1, Page 28-40, January 2026.
ABSTRACT Background and Aim Potassium‐competitive acid blockers (P‐CABs) are a novel class of acid suppressants developed to overcome the limitations of proton pump inhibitors (PPIs), providing rapid and sustained acid suppression. While PPI‐related adverse events (AEs) are well‐documented, safety data on P‐CABs remain limited.
Yewon Jang, Jongho Park, Dahee Kang, Jae Hyun Kim, Hyuk Soon Choi, Ha‐Lim Jeon, Hankil Lee   +6 more
wiley   +1 more source

Efficacy and safety of immune checkpoint inhibitors in advanced non-small cell lung cancer with idiopathic interstitial pneumonia or interstitial lung abnormalities: NJLCG2301. [PDF]

Transl Lung Cancer Res
Okumura F, Tanaka H, Onodera K, Morita R, Inomata M, Suzuki A, Sugisaka J, Minemura H, Jingu D, Kudo S, Kikuchi H, Yoshimura N, Tsushima F, Kakeda S, Tasaka S.   +14 more
europepmc   +1 more source

Deucravacitinib Improved Interstitial Pneumonia Along with KL-6 Reduction in a Patient with Psoriasis: A Case Report. [PDF]

Clin Cosmet Investig Dermatol
Mima Y, Ohtsuka T, Akiyama N, Norimatsu Y.   +3 more
europepmc   +1 more source

Pharmacokinetics of Ampicillin Trihydrate in Plasma, Interstitial, and Peritoneal Fluid Following Intraperitoneal or Intramuscular Administration in Steers at the Beginning of a Standing Flank Laparotomy

Journal of Veterinary Pharmacology and Therapeutics, Volume 49, Issue 1, Page 44-54, January 2026.
ABSTRACT Prophylactic and perioperative use of antibiotics is common prior to abdominal surgery in cattle for minimizing the risk of postoperative infections. Yet, there is little information on drug concentrations at sites of potential infections following surgical procedures. The objective of this study was to compare the concentrations in the plasma,
Danielle A. Mzyk, Jennifer L. Halleran, Laura M. Neumann, Ronald E. Baynes, Derek M. Foster   +4 more
wiley   +1 more source

Usual Interstitial Pneumonia Pattern and Mycobacteria Lung Diseases: A Case Series. [PDF]

Infect Dis Rep
Licata MA, Monteleone G, Schiavi E, Musso M, Mencarini P, Mastrobattista A, Carli SM, Cerva C, Sgalla G, Richeldi L, Palmieri F, Gualano G.   +11 more
europepmc   +1 more source

Efficacy and Safety of Atezolizumab Plus Bevacizumab for Patients With Hepatocellular Carcinoma and Child–Pugh Class B

Liver International, Volume 46, Issue 1, January 2026.
ABSTRACT Background & Aims Despite the advances in systemic therapy for unresectable hepatocellular carcinoma (HCC), patients with Child–Pugh class B (CP‐B) liver function face a significant unmet need. This study evaluated the efficacy and safety of atezolizumab plus bevacizumab (Atez/Bev) in patients with unresectable HCC and CP‐B.
Ryu Sasaki, Shigeo Shimose, Issei Saeki, Takanori Ito, Yasuto Takeuchi, Joji Tani, Tetsu Tomonari, Kyo Sasaki, Satoru Kakizaki, Takeshi Hatanaka, Satoshi Miuma, Tomotake Shirono, Hideki Iwamoto, Norikazu Tanabe, Takafumi Yamamoto, Yuki Kanayama, Atsushi Naganuma, Sohji Nishina, Tetsuji Takayama, Hideki Kobara, Motoyuki Otsuka, Hiroki Kawashima, Taro Takami, Takumi Kawaguchi, Hisamitsu Miyaaki, Hepatology InVestigator Experts in Japan (HIVE‐J) Study Group   +25 more
wiley   +1 more source

Efficacy and safety of zuranolone in Japanese adults with major depressive disorder: A double‐blind, randomized, placebo‐controlled, Phase 3 clinical trial

Psychiatry and Clinical Neurosciences, Volume 80, Issue 1, Page 76-86, January 2026.
Aim To evaluate the efficacy and safety of oral zuranolone for 14 days, compared with placebo, in Japanese patients with major depressive disorder (MDD). Methods This multicenter, Phase 3 study was conducted in two parts (70 sites; Japan) including a randomized, double‐blind, placebo‐controlled, parallel‐group part presented herein.
Masaki Kato, Kazuyuki Nakagome, Takamichi Baba, Takuhiro Sonoyama, Hiroki Fukuju, Ryosuke Shimizu, Juan Carlos Gomez, Tomoko Motomiya, Takeshi Inoue   +8 more
wiley   +1 more source

Case Report: A case of interstitial pneumonia in a colorectal cancer patient with a history of lung cancer treated with cetuximab. [PDF]

Front Oncol
Yang Y, Zhang B, Li H, Ren M, Chong D, Guo Y, Zhao H, Yu QQ.   +7 more
europepmc   +1 more source