Results 91 to 100 of about 783,235 (315)

Sex Hormones Associate With Amyotrophic Lateral Sclerosis Risk and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) risk differs by sex and age, implicating sex hormones as potential modifiers. This study examined plasma levels of biologically active sex hormones and their association with ALS odds and survival in cases (females n = 131, males n = 189) and controls (females n = 138, males n = 150) from the University of ...
Stephen A. Goutman, David G. Stouffer, Dae‐Gyu Jang, Jihyun Park, Benjamin J. Murdock, Richard J. Auchus   +5 more
wiley   +1 more source

ICBoost: An XGBoost-Based Unbiased Transformed Algorithm for Survival Regression

IEEE Access
Prediction models for disease onset are critical in biomedical research and survival analysis. With machine learning methods increasingly being used to handle survival data with censoring, unbiased transformation theory offers an alternative method for ...
Jingyi Zhang, Shishun Zhao, Yang Xu, Tao Hu   +3 more
doaj   +1 more source

Jackknife and bootstrap inferential procedures for censored survival data [PDF]

, 2014
Confidence interval is an estimate of a certain parameter. Classical construction of confidence interval based on asymptotic normality (Wald) often produces misleading inferences when dealing with censored data especially in small samples.
Abu Bakar, Mohd Rizam, Arasan, Jayanthi, Loh, Yue Fang, Midi, Habshah   +3 more
core   +1 more source

Experimental Survival Curves for Interval-Censored Data

Applied Statistics, 1973
A method is given for calculating from interval‐censored data an estimate of the c.d.f. which is analogous to the estimate derivable from right‐censored data by the life‐table technique. A Fortran implementation has been constructed by the author.
openaire   +2 more sources

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

HIV dynamics and natural history studies: Joint modeling with doubly interval-censored event time and infrequent longitudinal data

, 2011
Hepatitis C virus (HCV) coinfection has become one of the most challenging clinical situations to manage in HIV-infected patients. Recently the effect of HCV coinfection on HIV dynamics following initiation of highly active antiretroviral therapy (HAART)
Hogan, Joseph W., Su, Li
core   +1 more source

Geoadditive hazard regression for interval censored survival times [PDF]

, 2005
The Cox proportional hazards model is the most commonly used method when analyzing the impact of covariates on continuous survival times. In its classical form, the Cox model was introduced in the setting of right-censored observations.
Kneib, Thomas
core   +4 more sources

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller, Lauren N. Coffey, Shelley R. H. Mockler, Katie M. Laubscher, Carrie M. Stephan, M. Bridget Zimmerman, Katherine D. Mathews   +6 more
wiley   +1 more source

Association of CDKN2A/B Homozygous Deletion and Extent of Resection With Survival of Patients With WHO CNS5 Grade 4 Astrocytoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives WHO grade 4 astrocytomas are associated with poor prognosis, and their prognostic factors remain controversial. This study aimed to identify the prognostic factors and develop a management algorithm for these patients. Methods This study retrospectively included 151 CNS5 adult grade 4 astrocytomas from two medical centers.
Jiawei Cai, Guanglin Zhu, Qiu He, Chen Luo, Lingyun Zhuo, Xingfu Wang, Yiming Chen, Xiaoyong Chen, Wendong You, Jiaheng Xu, Yuanxiang Lin, Dezhi Kang, Shuai Wu, Zanyi Wu   +13 more
wiley   +1 more source

Observed Range Maximum Likelihood Estimation [PDF]

, 2011
The idea of maximizing the likelihood of the observed range for a set of jointly realized counts has been employed in a variety of contexts. The applicability of the MLE introduced in [1] has been extended to the general case of a multivariate sample ...
Markov, Plamen
core