Results 221 to 230 of about 5,209,352 (294)

Benznidazole therapy improves pressure overload and cardiac electrical profile in an experimental model of Angiotensin II infusion-induced hypertension: Mechanistic insights. [PDF]

PLoS One
da Silva Pinheiro P, Vilar-Pereira G, Castaño-Barrios L, Peroba Rezende Ramos I, Pedra-Rezende Y, Dantas-Pereira L, Figueiredo Sadok Menna-Barreto R, Gibaldi D, Mata-Santos HA, Lannes-Vieira J.   +9 more
europepmc   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Hypothalamic deiodinase type-3 establishes the period of circannual interval timing in mammals. [PDF]

Elife
Stewart C, Liddle TA, Tolla E, Lewis JE, Marshall C, Evans NP, Morgan PJ, Ebling FJP, Stevenson TJ.   +8 more
europepmc   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Optimal doses of high-intensity interval training in patients with coronary artery disease and heart failure: a systematic review and meta-analysis. [PDF]

Front Cardiovasc Med
Wu Y, Wang H.
europepmc   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Changes of the cardiac electrical cycle in type 1 diabetes during hypoglycaemia - a prospective observational study. [PDF]

Front Endocrinol (Lausanne)
Kézdi Á, Horváth VJ, Vass V, Svébis MM, Kocsis G, Ferencz V, Jávorfi T, Domján BA, Tabák ÁG.   +8 more
europepmc   +1 more source

Impact of postoperative surveillance via computed tomography after radical resection for thymoma. [PDF]

Mediastinum
Maru N, Hino H, Utsumi T, Kobayashi A, Fukumoto K, Matsui H, Taniguchi Y, Saito T, Murakawa T.   +8 more
europepmc   +1 more source

The FIB-4 Index Is Independently Associated with QTc Interval in Patients with Ankylosing Spondylitis. [PDF]

J Clin Med
Ergül E, Durak H, Çetin M, Duman H, Emlek N, Yılmaz AS, Özyıldız AG, Barutçu G, Cüre O.   +8 more
europepmc   +1 more source