Results 91 to 100 of about 222,312 (289)

Effect of carbamazepine on the pharmacokinetics of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader, in healthy adults

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim To evaluate the effects of carbamazepine, a strong cytochrome P450 (CYP)3A4 inducer, on the pharmacokinetics and safety of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader. Methods This was a phase 1, open‐label, fixed‐sequence, two‐period study in healthy adult participants.
Hechuan Wang   +7 more
wiley   +1 more source

MSB-First Interval-Bounded Variable-Precision RealTime Arithmetic Unit

open access: yesJournal of ICT Research and Applications, 2013
This paper presents a paradigm of real-time processing on the lowest level of computing systems: the arithmetic unit. The arithmetic unit based on this principle containing addition, subtraction, multiplication and division operations is  described.  The 
Yusrila Y. Kerlooza   +2 more
doaj  

Factored Notation for Interval I/O

open access: yes, 2001
This note addresses the input and output of intervals in the sense of interval arithmetic and interval constraints. The most obvious, and so far most widely used notation, for intervals has drawbacks that we remedy with a new notation that we propose to ...
van Emden, M. H.
core  

The Impact of Sustainability Orientation and Sustainability Challenges in SME Responses to Institutional Support

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT SMEs receive increasing institutional support to embed sustainability, yet they vary widely in their ability to translate such support into practice. This study addresses this gap by examining the internal cognitive and strategic mechanism (sustainability orientation) through which managers interpret institutional support and the contextual ...
Michael Zisuh Ngoasong   +3 more
wiley   +1 more source

A variant of the Bombieri-Vinogradov theorem in short intervals with applications

open access: yes, 2015
We generalize the classical Bombieri-Vinogradov theorem to a short interval, non-abelian setting. This leads to variants of the prime number theorem for short intervals where the primes lie in arithmetic progressions that are "twisted" by a splitting ...
Thorner, Jesse
core   +1 more source

Optimization of Lithium‐Ion Battery Circular Economy in Electric Vehicles in Sustainable Supply Chain

open access: yesBattery Energy, Volume 4, Issue 2, March 2025.
Lithium batteries constitute a pivotal component in electric vehicles (EVs) owing to their rechargeability and high‐power output capabilities. ABSTRACT Lithium batteries constitute a pivotal component in electric vehicles (EVs) owing to their rechargeability and high‐power output capabilities.
Mohsen Alizadeh Afroozi   +4 more
wiley   +1 more source

Guaranteed parameter estimation in nonlinear dynamic systems using improved bounding techniques [PDF]

open access: yes, 2013
This paper is concerned with guaranteed parameter estimation in nonlinear dynamic systems in a context of bounded measurement error. The problem consists of finding - or approximating as closely as possible - the set of all possible parameter values such
Chachuat, B   +3 more
core  

Application of Ultrasonic Sensors for Determining the Height of Dynamic Two‐Phase Layers in Tray Columns

open access: yesChemie Ingenieur Technik, EarlyView.
Ultrasonic sensors are evaluated for their applicability in dynamic gas–liquid systems. By comparing sensor data with two independent optical reference methods, their robustness and reliability are demonstrated under varying flow conditions and tray geometries in column systems.
Niklas Breuer   +2 more
wiley   +1 more source

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