Results 81 to 90 of about 1,743,511 (277)
, 2003 Norm estimates are developed between the Bochner integral of a vector-valued function in Banach spaces having the Radon-Nikodym property and the convex combination of function values taken on a division of the interval [a,b]
Cerone, P. +4 more
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Linking denitrification with ecosystem respiration in mountain streams
Limnology and Oceanography Letters, 2019 Rivers denitrify a portion of their nitrate (NO3−) load, but estimates are difficult using microcosm or reach‐scale measurements that require specific biogeochemical and hydrologic conditions.
Hilary L. Madinger, Robert O. Hall Jr.
doaj +1 more source
Improving point and interval estimates of monotone functions by rearrangement [PDF]
Suppose that a target function is monotonic, namely weakly increasing, and an original estimate of this target function is available, which is not weakly increasing. Many common estimation methods used in statistics produce such estimates.
Alfred Galichon +2 more
core
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Rational Choice of the Investment Project Using Interval Estimates of the Initial Parameters [PDF]
Problemi Ekonomiki, 2016 The article is dedicated to the development of instruments to support decision-making on the problem of choosing the best investment project in a situation when initial quantitative parameters of the considered investment alternatives are described by
Kotsyuba Oleksiy S.
doaj
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Revstat Statistical JournalThe purpose of the present paper is two-fold. First, we consider the estimation of the unknown model parameters and the reliability characteristics of a gamma-mixed Rayleigh distribution when a progressively type-II censored sample (PT-IICS) is ...
Kousik Maiti, Suchandan Kayal
doaj +1 more source