Stromal vascular fraction (SVF) may enhance nerve repair, especially when delivered in a self‐assembling peptide hydrogel (SAPH). In vitro, softer SAPH increased neuronal explant outgrowth and supported greater SVF viability and proliferation. In a rat sciatic defect, SVF in an optimized SAPH produced motor and sensory recovery equivalent to autograft ...
Liam A. McMorrow +6 more
wiley +1 more source
Large-scale causal discovery using interventional data sheds light on gene network structure in k562 cells. [PDF]
Brown BC +4 more
europepmc +1 more source
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement +12 more
wiley +1 more source
Efficacy and toxicity of neoadjuvant radiotherapy with concomitant dose escalation for rectal cancer. [PDF]
Wang P +7 more
europepmc +1 more source
A New Concept of Matrix Algorithm for MST in Undirected Interval Valued Neutrosophic Graph
Said Broumi +4 more
openalex +1 more source
Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins +3 more
wiley +1 more source
Prognostic significance of preoperative C-reactive protein-triglyceride-glucose index in long-term outcomes after radical gastrectomy for gastric cancer. [PDF]
Hao QL +7 more
europepmc +1 more source
A compact handheld GelSight probe reconstructs in vivo 3‐D skin topography with micron‐level precision using a custom elastic gel and a learning‐based surface normal to height map pipeline. The device quantifies wrinkle depth across various body locations and detects changes in wrinkle depth following moisturizer application.
Akhil Padmanabha +12 more
wiley +1 more source
Effects of repeated low-level red light on refractive development during childhood: a systematic review and dose-response meta-analysis up to 12 months. [PDF]
Ren Q, Chu Z, Qiu Z, Cheng H, Liu L.
europepmc +1 more source
A Biomimetic Buffering Hydrogel Scaffold for Long‐Term Culture of Patient‐Derived Tumor Organoids
A biomimetic fibrous buffering hydrogel controls the local acidification at the tumoroid/hydrogel interface at the physiologically relevant level over 21‐day culture. The buffering effect promotes cancer cell proliferation in the tumoroids and supports the structural integrity and mechanical properties of the hydrogel scaffold over long‐term tumoroid ...
Elizaveta Gusarova +5 more
wiley +1 more source

