Results 51 to 60 of about 3,018,719 (345)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Interval Graphs and Proper Interval Graphs in Fuzzy and Neutrosophic Graphs

open access: yesInformation Sciences with Applications
Interval graphs represent vertices as intervals on the real line, with edges denoting overlapping intervals, while proper interval graphs prevent one interval from being fully contained within another. This paper explores interval and proper interval graphs within the frameworks of fuzzy, neutrosophic, and Turiyam Neutrosophic graphs.
Takaaki Fujita, Florentin Smarandache
openaire   +2 more sources

Dombi Interval Valued Neutrosophic Graph and its Role in Traffic Control Management [PDF]

open access: yesNeutrosophic Sets and Systems, 2019
An advantage of dealing indeterminacy is possible only with Neutrosophic Sets. Graph theory plays a vital role in the field of networking. If uncertainty exist in the set of vertices and edge then that can be dealt by fuzzy graphs in any application and ...
D. Nagarajan   +3 more
doaj   +1 more source

Signed interval graphs and bigraphs: A generalization of interval graphs and bigraphs

open access: yes, 2022
In this paper, we define and characterize signed interval graphs and bigraphs introducing the concept of negative interval. Also we have shown that these classes of graphs are respectively a generalization of well known classes of interval graphs and interval bigraphs.
Das, Ashok Kumar, Paul, Indrajit
openaire   +2 more sources

Interval k-Graphs and Orders [PDF]

open access: yesOrder, 2017
An interval $k$-graph is the intersection graph of a family $\mathcal{I}$ of intervals of the real line partitioned into at most $k$ classes with vertices adjacent if and only if their corresponding intervals intersect and belong to different classes.
Brown, David E.   +2 more
openaire   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

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