Results 51 to 60 of about 3,565,508 (299)

Dombi Interval Valued Neutrosophic Graph and its Role in Traffic Control Management [PDF]

Neutrosophic Sets and Systems, 2019
An advantage of dealing indeterminacy is possible only with Neutrosophic Sets. Graph theory plays a vital role in the field of networking. If uncertainty exist in the set of vertices and edge then that can be dealt by fuzzy graphs in any application and ...
D. Nagarajan, M.Lathamaheswari, S. Broumi, J. Kavikumar   +3 more
doaj   +1 more source

Simultaneous Interval Graphs [PDF]

, 2010
In a recent paper, we introduced the simultaneous representation problem (defined for any graph class C) and studied the problem for chordal, comparability and permutation graphs. For interval graphs, the problem is defined as follows. Two interval graphs G_1 and G_2, sharing some vertices I (and the corresponding induced edges), are said to be ...
Krishnam Raju Jampani, Anna Lubiw
openaire   +3 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Distance Two Surjective Labelling of Paths and Interval Graphs

Discrete Dynamics in Nature and Society, 2021
Graph labelling problem has been broadly studied for a long period for its applications, especially in frequency assignment in (mobile) communication system, X-ray crystallography, circuit design, etc.
Sk Amanathulla, G. Muhiuddin, D. Al-Kadi, Madhumangal Pal   +3 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Interval Incidence Coloring of Subcubic Graphs

Discussiones Mathematicae Graph Theory, 2017
In this paper we study the problem of interval incidence coloring of subcubic graphs. In [14] the authors proved that the interval incidence 4-coloring problem is polynomially solvable and the interval incidence 5-coloring problem is NP-complete, and ...
Małafiejska Anna, Małafiejski Michał
doaj   +1 more source

On the on-line coloring of unit interval graphs with proper interval representation [PDF]

Discrete Mathematics & Theoretical Computer Science
We define the problem as a two-player game between Algorithm and Builder. The game is played in rounds. Each round, Builder presents an interval that is neither contained in nor contains any previously presented interval.
Israel R. Curbelo, Hannah R. Malko
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Steiner intervals in graphs

Discrete Applied Mathematics, 1998
If \(S\) is a subset of the vertex set of a connected graph \(G\), then the Steiner distance \(d(S)\) of \(S\) is the minimum number of edges of a connected subgraph of \(G\) that contains \(S\); this subgraph is always a tree and is called a Steiner tree for \(S\). The Steiner interval \(I(S)\) of \(S\) is the set of all vertices of \(G\) which lie in
Ewa M. Kubicka, Grzegorz Kubicki, Ortrud Oellermann   +2 more
openaire   +3 more sources