Results 51 to 60 of about 588,772 (275)

Graph isomorphism completeness for trapezoid graphs

, 2015
The complexity of the graph isomorphism problem for trapezoid graphs has been open over a decade. This paper shows that the problem is GI-complete. More precisely, we show that the graph isomorphism problem is GI-complete for comparability graphs of ...
Takaoka, Asahi
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

EnGS-DGR: Traffic Flow Forecasting with Indefinite Forecasting Interval by Ensemble GCN, Seq2Seq, and Dynamic Graph Reconfiguration [PDF]

, 2022
Shiyuan Han, Qiang Zhao, Qi-Wei Sun, Jin Zhou, Yuehui Chen   +4 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Nodal domains on quantum graphs

, 2003
We consider the real eigenfunctions of the Schr\"odinger operator on graphs, and count their nodal domains. The number of nodal domains fluctuates within an interval whose size equals the number of bonds $B$.
Aurich R, Aurich R, Barra F, Berkolaiko G, Berkolaiko G, Berry M, Berry M V, Berry M V, Bies W E, Blum G, Bogomolny E, Courant R, Courant R, Courant R, Foltin G, Gradsteyn I S, Gutzwiller M C, Haake F, Joachim Weber, Kottos T, Monastra A G, Pleijel A, Simmel F, Stratt R M, Sven Gnutzmann, Uzy Smilansky   +25 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

A polynomial algorithm for the k-cluster problem on interval graphs

, 2008
This paper deals with the problem of finding, for a given graph and a given natural number k, a subgraph of k nodes with a maximum number of edges. This problem is known as the k-cluster problem and it is NP-hard on general graphs as well as on chordal ...
Mertzios, George B.
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Weakly toll convexity and proper interval graphs [PDF]

Discrete Mathematics & Theoretical Computer Science
A walk $u_0u_1 \ldots u_{k-1}u_k$ is a \textit{weakly toll walk} if $u_0u_i \in E(G)$ implies $u_i = u_1$ and $u_ju_k\in E(G)$ implies $u_j=u_{k-1}$. A set $S$ of vertices of $G$ is {\it weakly toll convex} if for any two non-adjacent vertices $x,y \in S$
Mitre C. Dourado, Marisa Gutierrez, Fábio Protti, Silvia Tondato   +3 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source