Results 51 to 60 of about 157,845 (305)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The niche graphs of interval orders
Discussiones Mathematicae Graph Theory, 2014 The niche graph of a digraph D is the (simple undirected) graph which has the same vertex set as D and has an edge between two distinct vertices x and y if and only if N+D(x) ∩ N+D(y) ≠ ∅ or N−D(x) ∩ N−D(y) ≠ ∅, where N+D(x) (resp.
Park Jeongmi, Sano Yoshio
doaj +1 more source
On the Representation of a PI-Graph
Trends in Computational and Applied Mathematics, 2007 Consider two parallel lines (denoted r1 and r2). A graph is a PI graph (Point-Interval graph) if it is an intersection graph of a family F of triangles between r1 and r2 such that each triangle has an interval with two endpoints on r1 and a vertex (a ...
S.M. Almeida, C.P. de Mello, A. Gomide
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Equivalence of the filament and overlap graphs of subtrees of limited trees [PDF]
Discrete Mathematics & Theoretical Computer Science, 2017 The overlap graphs of subtrees of a tree are equivalent to subtree filament graphs, the overlap graphs of subtrees of a star are cocomparability graphs, and the overlap graphs of subtrees of a caterpillar are interval filament graphs.
Jessica Enright, Lorna Stewart
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Interval Valued Neutrosophic Soft Graphs
, 2018 In this article, we combine the interval valued neutrosophic soft set and graph theory. We introduce the notions of interval valued neutrosophic soft graphs, strong interval valued neutrosophic graphs, complete interval valued neutrosophic graphs, and ...
Florentin Smarandache (4496650) +4 more
core +2 more sources
, 1982 In this paper we enumerate interval graphs (up to isomorphism) along with labelled interval graphs, identity interval graphs, transitive interval graphs and various sorts of unit interval graphs. The enumeration makes use of a structural decomposition of
Phil Hanlon
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source