Results 61 to 70 of about 2,985,813 (306)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
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Interval Weighted Comparison Matrices – A Review
International Journal of Industrial Engineering and Production Research, 2010 Nowadays, interval comparison matrices (ICM) take an important role in decision making under uncertainty. So it seems that a brief review on solution methods used in ICM should be useful. In this paper, the common methods are divided into four categories
Masoud Narenji +2 more
doaj
Variation diminution and intervals of sign regular matrices
Results in Applied MathematicsA sign regular matrix is a matrix having the property that its non-zero minors of all orders have, for each order, an identical sign. Such matrices arise in a wide range of applications. In this paper, intervals of real matrices with respect to the usual
Mohammad Adm, Jürgen Garloff
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
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Positive Hankel Matrices, Eigenvalues and Total Positivity
MathematicsFor positive Hankel matrices, an interval containing all eigenvalues is obtained. With a stronger condition, we also construct two sharper intervals for the eigenvalue localization. The total positivity of positive Hankel matrices is analyzed.
Juan Manuel Peña
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European Journal of Operational Research, 2016 Existing research on acceptability of pairwise interval comparison matrices focuses on acceptable consistency by controlling their inconsistency levels to within a certain threshold.
Kevin W. Li, Zhou-Jing Wang, Xiayu Tong
semanticscholar +1 more source
The interval structure of \(( 0 , 1 )\)-matrices
Discret. Appl. Math., 2018 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Richard A. Brualdi, Geir Dahl
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
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Matrix measure and application to stability of matrices and interval dynamical systems
International Journal of Mathematics and Mathematical Sciences, 2003 Using some properties of the matrix measure, we obtain a general condition for the stability of a convex hull of matrices that will be applied to study the stability of interval dynamical systems.
Ziad Zahreddine
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