Results 91 to 100 of about 2,138,473 (247)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The number of cube-full numbers in an interval [PDF]
Acta Arithmetica, 1994 Let \(Q_ 3(x)\) denote the number of cube-full integers not exceeding \(x\). A natural number is called cube-full if \(p\mid n\) implies \(p^ 3\mid n\), where \(p\) denotes a prime. It is useful to investigate the number of cube-full integers in short intervals \((x, x^{2/3+\mu}]\), \(\mu< 1/3\), and to search for an asymptotic relation \[ Q_ 3(x+ x^{2/
openaire +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
International Journal of Applied Mathematics and Computer Science, 2017 In a real world situation, whenever ambiguity exists in the modeling of intuitionistic fuzzy numbers (IFNs), interval valued intuitionistic fuzzy numbers (IVIFNs) are often used in order to represent a range of IFNs unstable from the most pessimistic ...
Vidhya Rajendran +1 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Croatian Operational Research Review, 2015 This paper proposes a differential equation inventory model that incorporates partial backlogging and deterioration. Holding cost and demand rate are time dependent. Shortages are allowed and assumed to be partially backlogged. Two versions are presented,
Debashis Dutta, Pavan Kumar
doaj +1 more source
Interval numbers of powers of block graphs
Discrete Mathematics, 2004 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Mingjang Chen +2 more
openaire +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Small interval interpolation fitting bootstrapping method based on residue number system
Xibei Gongye Daxue XuebaoAiming at the problem that the bootstrapping time of approximate homomorphic encryption scheme is too long, a small interval interpolation fitting method based on residue system is proposed.
LI Huixian +4 more
doaj +1 more source