Results 51 to 60 of about 96,590 (303)
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Eyewitness accuracy and retrieval effort: Effects of time and repetition.
An important task for the law enforcement is to assess the accuracy of eyewitness testimonies. Recent research show that indicators of effortful memory retrieval, such as pausing and hedging (e.g. "I think", "maybe"), are more common in incorrect recall.
Philip U Gustafsson +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Background: Maximum repetitions to failure (RTF) and repetitions in reserve (RIR) can be estimated through fastest mean velocity (MV fastest ) and mean velocity (MV), respectively.
Carlos Martínez-Rubio +4 more
openaire +3 more sources
Effect of rest interval length on repeated 1 repetition maximum back squats.
To examine the effects of different rest intervals on the repeatability of 1 repetition maximum (IRM) efforts in the free-weight back squat exercise, 17 weight-trained men served as subjects (mean age 22.0 years).
MARVIN M. MCKNIGHT +9 more
core +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Time-Based Transition Expectancy in Task Switching: Do We Need to Know the Task to Switch to?
Recent research has shown that humans are able to implicitly adapt to time-transition contingencies in a task-switching paradigm, indicated by better performance in trials where the task transition (switch vs.
Stefanie Aufschnaiter +2 more
doaj +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source

