Results 81 to 90 of about 6,127,722 (370)

Study protocol: a randomised controlled trial investigating the effect of exercise training on peripheral blood gene expression in patients with stable angina [PDF]

, 2010
Background: Exercise training has been shown to reduce angina and promote collateral vessel development in patients with coronary artery disease. However, the mechanism whereby exercise exerts these beneficial effects is unclear.
A Bye, AJ Vickers, AT Beck, AT Beck, CJ Lavie, David C Crossman, G Borg, G Sanguinetti, GA Lancaster, Garry A Tew, GK Hansson, IM Packham, JA Jolliffe, JA Spertus, JA Wingrove, John M Saxton, Liam Bourke, M Billinger, Marta Milo, P Meier, PD Thompson, PR Sinnaeve, R Hambrecht, R Hambrecht, R Zbinden, RD Pearson, RS Taylor, S Senti, Timothy JA Chico, TW Chittenden, V Froelicher, W Schaper   +31 more
core   +4 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

The effect of 8 weeks of interval training combined with the consumption of cineole, linalool, and bourbonene on MAPK/Arc gene expression and learning in rats with Alzheimer’s disease [PDF]

Journal of Shahrekord University of Medical Sciences
Background and aims: This research aimed to investigate the effect of 8 weeks of interval training and the use of cineole, linalool, and bourbonene on MAPK/Arc gene expression and learning in Alzheimer’s disease (AD) rats.
Elham Majidi, Khosro Jalali Dehkordi, Farzaneh Taghian, Seyed Ali Hosseini   +3 more
doaj   +1 more source

HORMONAL RESPONSE TO DIFFERENT REST INTERVALS DURING RESISTANCE TRAINING WITH LIGHT LOADS [PDF]

Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2014
Purpose: The purpose of the present study was to determine the appropriate rest time between sets during weight training with light load. Material: Seventeen cadet wrestlers (age =16.7±0.6 yrs.; height =169.2±8.2 cm; and weight =51.4±7.9 kg) were ...
Payam Mohamad-Panahi, Hadi Rohani, Navid Lotfi   +2 more
doaj   +1 more source

'Functional' inspiratory and core muscle training enhances running performance and economy. [PDF]

, 2014
We compared the effects of two 6-week high-intensity interval training interventions. Under the control condition (CON), only interval training was undertaken, whilst under the intervention condition (ICT), interval training sessions were followed ...
Lin, H., McConnell, Alison K., Nie, J., Tong, T.K., Wang, J., Zhang, H.   +5 more
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

The Effect of Eight Weeks of Intermittent Rehabilitation Training with Quercetin ‎Nanoliposome on the Apoptotic Indices of P38 and MK2 in Male Rats with Isoproterenol ‎Induced Myocardial Infarction Model [PDF]

Journal of Paramedical Science and Rehabilitation
Purpose:Quercetin is effective in the rehabilitation and treatment of apoptosis caused by cardiac ischemia, however, due to its low solubility in water, it is not suitable for clinical application, which can be improved by turning it into nanoparticles ...
S Ahmadi, F Taghian, Kh Jalali Dehkordi, M Kargar Fard   +3 more
doaj   +1 more source

A Multi-Center Comparison of O2peak Trainability Between Interval Training and Moderate Intensity Continuous Training

Frontiers in Physiology, 2019
There is heterogeneity in the observed O2peak response to similar exercise training, and different exercise approaches produce variable degrees of exercise response (trainability).
Camilla Williams, B. Gurd, Jacob T. Bonafiglia, S. Voisin, Zhixiu Li, N. Harvey, Ilaria Croci, Jenna L. Taylor, T. Gajanand, Joyce S. Ramos, R. Fassett, J. Little, M. Francois, C. Hearon, S. Sarma, Sylvan L J E Janssen, E. V. Van Craenenbroeck, P. Beckers, V. Cornelissen, N. Pattyn, E. Howden, S. Keating, A. Bye, D. Stensvold, U. Wisløff, I. Papadimitriou, Xu Yan, D. Bishop, N. Eynon, J. Coombes   +29 more
semanticscholar   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Current aspects of high-intensity interval training for older adults: a narrative review

Journal of Physical Fitness and Sports Medicine, 2022
Negative aspects of aging include a decrease in muscle mass/strength and maximal oxygen consumption (VO2max). The most beneficial and adaptable protocol among the various exercise methods should be explored in older adults.
Shigenori Ito
doaj   +1 more source