Results 91 to 100 of about 4,008,724 (388)
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Effectiveness of clinician client centered counseling on condom use and status disclosure of adult HIV positive patients enrolled in care in Yola, Nigeria: a randomized clinical trial [PDF]
This study assessed the effectiveness of a developed and implemented Clinician Client Centered Counseling Module on improving condom use and increasing HIV status disclosure to spouses and or sex partners of adult patients living with HIV enrolled in ...
Gyanchand Rampal, Lekhraj Rampal +6 more
core
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Background & Aim: Infertility is defined as inability to become pregnant with regular sexual intercourse for more than one year without using preventive methods. Infertility has negative effects on the quality of life of infertile couples.
Tayebeh Mokhtari Sorkhani +4 more
doaj
Tailored System to Deliver Behavioral Intervention and Manage Data in Randomized Trials
BackgroundThe integrity of behavioral intervention trials depends on consistent intervention delivery, and uniform, comprehensive process data collection.
Zheng, Hua +4 more
doaj +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat +18 more
wiley +1 more source
PENGARUH KONSELING TERHADAP PENGETAHUAN DAN SIKAP PEMBERIAN MP-ASI
Growth failure process started since the child was still in the womb. The success of growth process is determined by feeding practices. A total of 59% of Indonesian children aged 6-23 months were given food that inappropriate with the recommendations of ...
Margareta Fatimah Azzahra +1 more
doaj +1 more source
Which smoking cessation interventions work best? [PDF]
Nicotine replacement therapy (NRT), bupropion, nortriptyline, clonidine, and varenicline are all effective, although insufficient evidence exists to recommend one intervention over another (SOR: A, systematic reviews).
Flake, Donna +4 more
core

