Results 101 to 110 of about 511,950 (315)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Efektivitas Pelatihan Program Kelompok “Aji” Pada Guru Bimbingan Dan Konseling [PDF]

open access: yes, 2000
AJI (Adventurous Juvenile Intervention) is a training program designed for increasing group counseling skill in a natural setting by using “learning by doing” and “experiential learning” principle.
Afiatin, T. (Tina)   +2 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

An Evidence-Based Violence Prevention Curriculum for Elementary School Children [PDF]

open access: yes, 2004
Poynton and Dimmitt present a brief overview and analysis of the article, Effectiveness of a violence prevention curriculum among children in elementary school: A randomized controlled trial, originally published in Journal of the American Medical ...
Dimmitt, Carey, Poynton, Tim
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Individual and Group Psycho-Educational Counseling on Knowledge, Attitude and Preference for Birth Method in Nulliparous Women: A Randomized Controlled Trial

open access: yesJournal of Family and Reproductive Health, 2018
Objective: To study the effects of the Individual and Group Psycho-educational counseling in pregnant women on knowledge, attitude and mode of delivery.
Mahnaz Nosratabadi   +3 more
doaj  

Counseling and Psychotherapy Within and Across Faith Traditions (Chapter 17 in The Oxford Handbook of the Psychology of Spirituality)

open access: yes, 2012
This chapter begins with general considerations for religiously and spiritually oriented psychotherapy, including the importance of seeing religion and spirituality as d.imensions of cultural diversity, considering clients\u27 welfare and autonomy, and ...
McMinn, Mark R
core  

The Lessons of Meta-Analysis: Does Group Counseling with Children and Adolescents Make a Difference? [PDF]

open access: yes, 2005
Carey and Dimmitt present a brief overview and analysis of the article, Evaluating the effectiveness of child and adolescent group treatment: A meta-analytic review, originally published in Journal of Clinical Child Psychology.
Carey, Jay, Dimmitt, Carey
core   +1 more source

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