Results 61 to 70 of about 3,571,652 (340)

A working model for cytoplasmic assembly of H/ACA snoRNPs

FEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Counseling on injectable contraception and HIV risk: Evaluation of a pilot intervention in Tanzania.

PLoS ONE, 2020
In a context of high rates of HIV prevalence, concerns over hormonal contraceptive use and the potential for increased risk of HIV acquisition have led to increased attention to counseling messages, particularly for users of the injectable.
Janine Barden-O'Fallon, Jennifer Mason, Emmanuel Tluway, Gideon Kwesigabo, Egidius Kamanyi   +4 more
doaj   +1 more source

Poedji Rochjati Score Card as Media for Preconception Counseling

Folia Medica Indonesiana, 2021
Highlight:• The PCC counseling effect using Poedji Rochjati Score Card (PRSC) on premarital knowledge about high-risk pregnancies was studied. • PRSC for preconception counseling is effective for women to improve knowledge about high-isk pregnancy ...
Naomy Simanungkalit, Samsriyaningsih Handayani, Muhammad Ilham Aldika Akbar   +2 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Beyond intention-to-treat: The effect of brief counseling for tobacco cessation in secondary analyses of a cluster randomized controlled trial in Swedish dental clinics

Contemporary Clinical Trials Communications, 2017
In experimental studies the assigned intervention measures the received intervention if full protocol adherence is achieved, but this is rarely the case in public health.
Sinziana I. Oncioiu, Livia Franchetti-Pardo, Suvi E. Virtanen, Fabrizio Faggiano, Maria R. Galanti   +4 more
doaj   +1 more source

Psychological and counselling interventions for female genital mutilation [PDF]

International Journal of Gynecology & Obstetrics, 2017
AbstractWomen and girls living with female genital mutilation (FGM) are more likely to experience psychological problems than women without FGM. As well as psychological support, this population may need additional care when seeking surgical interventions to correct complications of FGM.
Helen Smith, Karin Stein
openaire   +2 more sources

Psychological and Educational Intervention to Improve Tuberculosis Treatment Adherence in Ethiopia Based on Health Belief Model: A Cluster Randomized Control Trial

PLoS ONE, 2016
Background Treatment non-adherence results in treatment failure, prolonged transmission of disease and emergence of drug resistance. Although the problem widely investigated, there remains an information gap on the effectiveness of different methods to ...
H. Tola, D. Shojaeizadeh, A. Tol, G. Garmaroudi, M. Yekaninejad, A. Kebede, Luche Tadesse Ejeta, D. Kassa, E. Klinkenberg   +8 more
semanticscholar   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Effectiveness of solution-focused counseling therapy on pregnancy anxiety and fear of childbirth: A randomized clinical trial

Nursing Practice Today, 2021
Background & Aim: Fear of childbirth and pregnancy anxiety may affect the desire for normal delivery. No study has investigated the effectiveness of solution-focused counseling on either pregnancy anxiety or all factors comprising fear of childbirth.
Forough Mortazavi, Maryam Mehrabadi, Razieh Karrabi   +2 more
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source