Results 171 to 180 of about 1,819,629 (315)

Connect Kits for Family Action: Intervention Development and Exploratory Data Analysis of Proximal Outcomes. [PDF]

J Child Adolesc Subst Use
Komro KA, Skinner JR, Ivanich E, Barry CM, Jagtiani A, Livingston BJ, Talavera-Brown SL, LaBounty H, Gassaway AN, Livingston MD.   +9 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

A Culturally Congruent Psychosocial Intervention for Latino Caregivers of Children with Cancer: Intervention Development. [PDF]

Children (Basel)
Torres L, Campos B, Cortes H, Morales S, Lin C, Torno L, Kain ZN, Fortier MA.   +7 more
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Intervention development to reduce sedentary behaviour among adults: a qualitative investigation using the Behaviour Change Wheel. [PDF]

Int J Behav Nutr Phys Act
Harsanyi H, Slot N, Parkinson R, Morielli AR, Jeyapalan A, Holmes E, Flynn S, Campbell T, Quan H, Zeng Y, Yang J, Singh S, Vena J, Biddle S, Friedenreich CM, Yang L.   +15 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Developing and Assessing the Acceptability of an Information Booklet for Patients in Surveillance for Abdominal Aortic Aneurysms: An Intervention Development Study. [PDF]

Health Expect
Grindell C, Hughes J, Lumley E, Elstone A, Hall J, Michaels J, Nasim A, Radley S, Shackley P, Smith NM, Stansby G, Wood E, O'Cathain A.   +12 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Preferences and Participation Factors of a Web-Based Mind–Body Intervention for Chronic Orofacial Pain: A Qualitative Study

Journal of Pain Research
Brenda C Lovette,1,2 Nadine Levey,1 Kozbi Bayne Cliff,1 Jafar Bakhshaie,1,2 Ronald Kulich,3 Hsinlin Thomas Cheng,2,4 Shuhan He,2,5 Ana-Maria Vranceanu,1,2 Jonathan Greenberg1,2 1Center for Health Outcomes and Interdisciplinary Research, Department of ...
Lovette BC, Levey N, Cliff KB, Bakhshaie J, Kulich R, Cheng HT, He S, Vranceanu AM, Greenberg J   +8 more
doaj  

A new cross-disciplinary model for early integration of palliative care for patients with incurable cancer - an intervention development study. [PDF]

BMC Palliat Care
Swenne J, Stie M, Hansen TF, Rasmussen B, Nielsen K, Søndergaard J, Nissen RD, Jensen LH.   +7 more
europepmc   +1 more source