Results 81 to 90 of about 626,120 (309)
Identifying the consequences of dynamic treatment strategies: A decision-theoretic overview
, 2010 We consider the problem of learning about and comparing the consequences of dynamic treatment strategies on the basis of observational data. We formulate this within a probabilistic decision-theoretic framework. Our approach is compared with related work
Dawid, A. Philip, Didelez, Vanessa
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Hemorrhoidal disease: what role can rectal artery embolization play?
Frontiers in SurgeryIntroductionHemorrhoidal artery embolization, also known as Emborrhoid, has emerged in recent years as a minimally invasive treatment option for patients with recurrent and unresponsive to medical therapies hemorrhoidal bleeding symptoms. We present here
Julien Panneau +15 more
doaj +1 more source
Indian Journal of Psychiatry, 2018 Over the past four decades, psychiatric social workers have been conducting group interventions for persons with substance use disorders at NIMHANS. In this article, the authors highlight the brief history of group therapy, differences between group therapy and group work, and purpose and indicators of group therapy.
Ezhumalai, Sinu +3 more
openaire +2 more sources
Penalized Estimation of Directed Acyclic Graphs From Discrete Data
, 2018 Bayesian networks, with structure given by a directed acyclic graph (DAG), are a popular class of graphical models. However, learning Bayesian networks from discrete or categorical data is particularly challenging, due to the large parameter space and ...
Fu, Fei, Gu, Jiaying, Zhou, Qing
core +2 more sources
The introduction of new interventional procedures in the British National Health Service : A qualitative study [PDF]
, 2010 Copyright © 2010 Elsevier Ireland Ltd.
Adrian M. Grant +9 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Technical note: Image guided internal fiducial placement for stereotactic radiosurgery (CyberKnife)
Indian Journal of Radiology and Imaging, 2011 Internal gold fiducials are necessary for tracking the translational and rotational movements of target lesions during stereotactic radiosurgery.
Govindarajan Janardan Mallarajapatna +6 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source