Results 261 to 270 of about 52,505 (294)

Tailorable bimetallic nanozyme mitigates intervertebral disc degeneration by inhibiting oxidative stress and inflammageing. [PDF]

Theranostics
Zhang A, Gao H, Chen X, Shi P, Cheng Z, Chen Y, Wu W, Wu W, Yang C, Zhang Y.   +9 more
europepmc   +1 more source

Exploring the molecular mechanisms underlying intervertebral disc degeneration by analysing multiple datasets. [PDF]

Sci Rep
Lin L, Li D, Cai G, Zheng G, Huang D, Liu H, Lin S, Zhao F.   +7 more
europepmc   +1 more source

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Intervertebral disc “dysgeneration”

The Spine Journal, 2015
Perspective
Luk, KDK, Samartzis, D
openaire   +6 more sources

Mechanobiology of the intervertebral disc

Biochemical Society Transactions, 2002
Intervertebral disc degeneration has been linked in humans to extreme spinal loading regimens. However, mechanisms by which spinal force influences disc cellularity, morphology and consequently biomechanical function are unclear. To gain insight into mechanobiological interactions within the disc, we developed an in vivo murine tail-compression model ...
Erika I. Palmer, Jeffrey C. Lotz, Adam H. Hsieh, Andrew J.L. Walsh, J. R. Chin   +4 more
openaire   +3 more sources

Modeling of Intervertebral Discs

Spine, 1980
A model with rotational symmetry of an intervertebral disc is studied. The nucleus pulposus is assumed to consist of an incompressible fluid, and the annulus fibrosus is modeled by 11 fiber layers with alternating fiber inclination. The spaces between the fiber layers are assumed to be filled with an incompressible fluid.
K B Broberg, H O von Essen
openaire   +3 more sources

Intervertebral Disc Arthroplasty

Spine, 2004
Review article of current knowledge of disc arthroplasty.To review the rationale for disc replacement, the general principles of design, and early clinical results.Disc arthroplasty is an emerging treatment for patients with disc degeneration. Its theoretical advantages are to maintain motion, decrease the incidence of adjacent segment degeneration ...
Jeffrey P. Rouleau, Paul A. Anderson
openaire   +3 more sources

Intervertebral Disc Prostheses

Spine, 2003
This article is based on a comprehensive review of the literature related to intervertebral disc prostheses.To compile an overview of the results and complications related to various types of lumbar and cervical disc replacements.A functional disc prosthesis has been sought since the 1950s. Although there were a few early attempts, disc replacement did
Donna D. Ohnmeiss, Richard D. Guyer
openaire   +3 more sources

Estrogens and the intervertebral disc

Menopause International, 2009
Intervertebral discs are an integral part of the vertebral column. It has been shown that menopause has a negative effect on bone and on intervertebral discs. Estrogen has a beneficial effect of preserving the health of collagen-containing tissues, including the intervertebral disc.
Yves Muscat-Baron, Mark Brincat, Jean Calleja-Agius   +2 more
openaire   +2 more sources

The Intervertebral Disc

JAMA: The Journal of the American Medical Association, 1971
Those interested in the human spine and its afflictions always welcome summaries of our present knowledge. In the initial chapters of this book, the authors lucidly summarize spine embryology, anatomy, and mechanics. An outline of pathology, biochemistry, and metabolic alterations during various stages of degenerative disk disease provides basic ...
openaire   +2 more sources