Results 1 to 10 of about 470,929 (344)

Intervertebral disk regeneration in a rat model by allopurinol–loaded chitosan/alginate hydrogel [PDF]

Biomolecules & Biomedicine, 2023
Intervertebral disk degeneration remains one of the most challenging health problems. In the current study, allopurinol was loaded into the chitosan nanoparticles and then incorporated into chitosan/alginate hydrogels and then further studied for its ...
Linhui Ye, Zengxin Gao, Saeed Rohani
doaj   +3 more sources

Advances and Prospects in Biomaterials for Intervertebral Disk Regeneration [PDF]

Frontiers in Bioengineering and Biotechnology, 2021
Low-back and neck-shoulder pains caused by intervertebral disk degeneration are highly prevalent among middle-aged and elderly people globally. The main therapy method for intervertebral disk degeneration is surgical intervention, including interbody ...
Chunxu Li, Qiushi Bai, Yuxiao Lai, Jingjing Tian, Jiahao Li, Xiaodan Sun, Yu Zhao   +6 more
doaj   +3 more sources

Influence of Age and Gender on Intervertebral Disk Degeneration and Height in the Thoracolumbar Spine [PDF]

Spine Surgery and Related Research, 2022
Introduction: Intervertebral disk degeneration is a universal and natural process. However, no reports have summarized anatomical age-related intervertebral disk height and disk degenerative changes in the thoracolumbar spine or examined sex-specific ...
Masaaki Machino, Hiroaki Nakashima, Keigo Ito, Mikito Tsushima, Kei Ando, Kazuyoshi Kobayashi, Shiro Imagama   +6 more
doaj   +3 more sources

Intervertebral Disk Degeneration: The Microenvironment and Tissue Engineering Strategies [PDF]

Frontiers in Bioengineering and Biotechnology, 2021
Intervertebral disk degeneration (IVDD) is a leading cause of disability. The degeneration is inevitable, and the mechanisms are complex. Current therapeutic strategies mainly focus on the relief of symptoms, not the intrinsic regeneration of the ...
Yiming Dou, Xun Sun, Xinlong Ma, Xin Zhao, Qiang Yang   +4 more
doaj   +3 more sources

Cytokine Imbalance as a Biomarker of Intervertebral Disk Degeneration. [PDF]

Int J Mol Sci, 2023
The intervertebral disk degeneration (IDD) and its associated conditions are an important problem in modern medicine. The onset of IDD may be in childhood and adolescence in patients with a genetic predisposition.
Shnayder NA, Ashhotov AV, Trefilova VV, Nurgaliev ZA, Novitsky MA, Vaiman EE, Petrova MM, Nasyrova RF.   +7 more
europepmc   +2 more sources

Clinical and magnetic resonance imaging characteristics of thoracolumbar intervertenral disk extrusions and protrusions in large breed dogs [PDF]

Veterinary Radiology & Ultrasound, 2002
It has recently been shown that the fat-derived hormone adiponectin has the ability to decrease hyperglycemia and to reverse insulin resistance. However, bacterially produced full-length adiponectin is functionally inactive. Here, we show that endogenous
Beltran, E, De Decker, S, Gomes, S A, Kenny, P J, Packer, R M A, Volk, H A   +5 more
core   +4 more sources

Prevalence and Risk Factors for Presumptive Ascending/Descending Myelomalacia in Dogs after Thoracolumbar Intervertebral Disk Herniation [PDF]

Journal of Veterinary Internal Medicine, 2017
Background: Ascending/descending myelomalacia (ADMM) is a severe complication of thoracolumbar intervertebral disk herniation (TL-IVDH) in dogs. Hypothesis/Objectives: To investigate the prevalence and risk factors for ADMM in nonambulatory dogs with ...
Aikawa, Amsellem, Bergknut, Bezuidenhout, Boekhoff, Ferreira, Fingeroth, Griffiths, Henke, Henke, Ito, Jeffery, Jeffery, Kato, Kranenburg, Lahunta, Laitinen, Levine, Lu, Marquis, Mayer, Muguet-Chanoit, Okada, Okada, Olby, Olby, Pais, Penning, Platt, Priester, Sato, Scott, Shinzato, Smolders, Zachary   +34 more
core   +2 more sources

Magnetic Resonance Imaging Signal Alterations in Paraspinal Muscles in Dogs with Acute Thoracolumbar Intervertebral Disk Extrusion

Frontiers in Veterinary Science, 2018
Muscle signal alteration detected on MRI is seen in diverse pathologic conditions. We observed signal alterations within the paraspinal muscles in dogs with acute thoracolumbar intervertebral disk extrusion.
Peter Trampus, Christine Goepfert, Monika Welle, Diana Henke, Franck Forterre, Daniela Schweizer-Gorgas   +5 more
doaj   +2 more sources

Does Calcium Phosphate Cement Kyphoplasty Cause Intervertebral Disk Degeneration in Adolescents? [PDF]

Cartilage, 2022
OBJECTIVE: Balloon kyphoplasty with polymethylmethacrylate (PMMA) represents the standard procedure for the treatment of thoracic and lumbar type A compression fractures.
Tschauner S, Singer G, Weitzer CU, Castellani C, Till H, Sorantin E, Wegmann H.   +6 more
europepmc   +3 more sources

Evaluation of magnetic resonance imaging guidelines for differentiation between thoracolumbar intervertebral disk extrusions and intervertebral disk protrusions in dogs [PDF]

Veterinary Radiology & Ultrasound, 2016
Four MRI variables have recently been suggested to be independently associated with a diagnosis of thoracolumbar intervertebral disk extrusion or protrusion.
Aikawa, Aikawa, Altman, Baltzer, Bergknut, Bergknut, Berknut, Besalti, Bos, Bray, Brisson, Brisson, Cihangiroglu, Cudia, da Costa, Decker, Decker, Decker, Downes, Fenn, Fisher, Flegel, Fleis, Gomes, Griffiths, Hansen, Knight, Landis, Lee, Macias, McKee, Modic, Moissonnier, Olby, Olby, Petersen, Rehman, Rihn, Robertson, Ruddle, Salger, Sander, Seiler, Sim, Smolders, Solgaard Sorensen, Song, Truszczyńska, Wie   +48 more
core   +2 more sources