Results 21 to 30 of about 22,569 (256)

Efficacy and Safety of Condoliase Disc Administration as a New Treatment for Lumbar Disc Herniation

Spine Surgery and Related Research, 2022
Introduction: Condoliase is a newly approved drug that improves symptoms associated with lumbar disk herniation (LDH) by intradiscal administration. This study aimed to evaluate the mid-term outcomes of condoliase injection, examine the adverse events ...
Masahiro Inoue, Takeshi Sainoh, Atsushi Kojima, Masatsune Yamagata, Tatsuo Morinaga, Chikato Mannoji, Hiromi Ataka, Masaomi Yamashita, Hiroshi Takahashi, Junya Saito, Takayuki Fujiyoshi, Tetsuhiro Ishikawa, Yawara Eguchi, Kei Kato, Sumihisa Orita, Kazuhide Inage, Yasuhiro Shiga, Masaki Norimoto, Tomotaka Umimura, Yuki Shiko, Yohei Kawasaki, Yasuchika Aoki, Seiji Ohtori   +22 more
doaj   +1 more source

Concept Development of a New Lumbar Intervertebral Disk Implant

MATEC Web of Conferences, 2017
Worldwide spinal cord injury incidence is rising, due to spikes in traffic incidences, violence and an increase in ageing population, prone to injuries. To satisfy an expanding market, a wide variety of spinal implantable devices are available.
Doicin Cristian-Vasile, Ulmeanu Mihaela-Elena, Frîncu Alexa-Sorina, Enache Vlad-Cristian   +3 more
doaj   +1 more source

Molecular Therapy for Disk Degeneration and Pain

Global Spine Journal, 2013
The nucleus pulposus of the intervertebral disk contains high amounts of the proteoglycan aggrecan, which confers the disk with a remarkable ability to resist compression. Other molecules such as collagens and noncollagenous proteins in the extracellular
Fackson Mwale PhD
doaj   +1 more source

Alkaptonuric patient presenting with “black” disc: a case report

Acta Orthopaedica et Traumatologica Turcica, 2020
Although intervertebral disc degeneration usually occurs in the natural course of alkaptonuria, detection of the disease by black disc material in a patient without any other sign of alkaptonuria is an extremely rare condition.
Ramazan Kahveci, Mehmet Fikret Ergungor, Ahmet Gunaydin, Atiye Temiz   +3 more
doaj   +1 more source

Clinical and magnetic resonance imaging characterization of cervical spondylomyelopathy in juvenile dogs

Journal of Veterinary Internal Medicine, 2019
Background Cervical spondylomyelopathy (CSM) occurs because of compression of the cervical spinal cord, nerve roots, or both, usually affecting young adult to older large and giant breed dogs. Juvenile dogs are affected infrequently.
Marília de AlbuquerqueBonelli, Ronaldo C. daCosta   +1 more
doaj   +1 more source

Exploration of High and Low Frequency Options for Subperception Spinal Cord Stimulation Using Neural Dosing Parameter Relationships: The HALO Study

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Subperception spinal cord stimulation (SCS) is described mostly utilizing waveforms that require high energy. However, the necessity of these waveforms for effective subperception has not been established. We aimed to explore whether effective subperception pain relief can be achieved using frequencies below 1 kHz.
José Paz‐Solís, Simon Thomson, Roshini Jain, Lilly Chen, Ismael Huertas, Que Doan   +5 more
wiley   +1 more source

Case report: Double adjacent ventral slot in two medium-sized breed dogs

Frontiers in Veterinary Science
Two medium-sized, 7-year-old dogs, with no previous history of pain, presented with acute neurologic symptoms consistent with intervertebral disk disease. Both cases had CT, where cervical pathology was identified.
Razvan Grigore Cojocaru, Bogdan Sicoe, Cristina Gaspar, Alexandra Grigoreanu, Gabriel Orghici, Ioan Tibru, Radu Lacatus   +6 more
doaj   +1 more source

Cell Adhesion by Design: Engineering Tissue Culture Scaffolds With Adhesion Cues

Advanced Materials Interfaces, EarlyView.
ABSTRACT In scaffold‐based tissue engineering, the matrix should provide adequate adhesion cues for cell attachment, spreading, and function. Given the multitude of adhesion receptors and the diversity of scaffolds, there are many approaches to render scaffolds adhesive, even though they are not all equivalent.
Dalia Dranseike, Dhananjay V. Deshmukh, Mark W. Tibbitt, Céline Labouesse   +3 more
wiley   +1 more source

Strategic Design of Soft Actuators in Translational Medical Robotics for Human‐Centered Healthcare

Advanced Robotics Research, EarlyView.
Soft robotics enables biocompatible, compliant medical devices, but clinical translation requires design‐driven engineering beyond materials. This perspective reviews implantable, surgical, and wearable systems by actuation mechanism, highlighting how optimized architectures and integration improve mechanical interfacing, adaptability, and durability ...
Ho Jun Jin, Jimin Kim, Inho Kim, Bong Hoon Kim   +3 more
wiley   +1 more source

Expression and Distribution of Interleukin-17 in Degenerated Human Cervical Intervertebral Disks

Global Spine Journal, 2012
Introduction To investigate the expression and distribution of interleukin-17 (IL-17) ingenerate human cervical intervertebral disks tissues and to explore the relationship between IL-l7 and cervical intervertebral disk degeneration.
Y. Zhang
doaj   +1 more source