Results 1 to 10 of about 664 (111)
Inflammatory Mediators in Intervertebral Disk Degeneration and Discogenic Pain
Global Spine Journal, 2013 Although degeneration of the intervertebral disk has historically been described as a misbalance between anabolic and catabolic factors, the role of inflammatory mediators has long been neglected.
Lisbet Haglund, Karin Wuertz
exaly +2 more sources
Overexpression of BNIP3 in rat intervertebral disk cells triggers autophagy and apoptosis [PDF]
Archives of Biological Sciences, 2022 Excessive apoptosis of intervertebral disk cells and intervertebral disk degeneration (IDD) is the prime cause of low back pain. B-cell lymphoma 2 (Bcl-2) and adenovirus E1B 19 kDa interacting protein 3 (BNIP3), a member of the Bcl-2 family, are involved
Tingsheng Wu +5 more
doaj +1 more source
Spine Surgery and Related Research, 2022 Introduction: Intervertebral disk degeneration is a universal and natural process. However, no reports have summarized anatomical age-related intervertebral disk height and disk degenerative changes in the thoracolumbar spine or examined sex-specific ...
Masaaki Machino +6 more
doaj +1 more source
Advances and Prospects in Biomaterials for Intervertebral Disk Regeneration
Frontiers in Bioengineering and Biotechnology, 2021 Low-back and neck-shoulder pains caused by intervertebral disk degeneration are highly prevalent among middle-aged and elderly people globally. The main therapy method for intervertebral disk degeneration is surgical intervention, including interbody ...
Chunxu Li +6 more
doaj +1 more source
Semi-automated spine and intervertebral disk detection and segmentation from whole spine MR images
Informatics in Medicine Unlocked, 2021 Intervertebral disks are found between the vertebrae in the spine from the second cervical vertebra to the sacrum. Intervertebral disks permit various movements of the vertebral column to keep it flexible and to absorb vertical shock.
Alaa Badarneh +3 more
doaj +1 more source
Clinical Practice and Cases in Emergency Medicine, 2021 Case Presentation: A five-year-old boy presented to our emergency department with severe posterior neck pain that was exacerbated upon neck movement. Cervical spine radiography revealed calcification in the cervical intervertebral disk 3–4.
Hirofumi Ohno +4 more
doaj +1 more source
Correlation among Inflammatory Cytokine Expression Levels, Degree of Disk Degeneration, and Predominant Clinical Symptoms in Patients with Degenerated Intervertebral Discs [PDF]
Asian Spine Journal, 2017 Study DesignObservational study.PurposeTo assess the correlation among inflammatory cytokine expression levels, degree of intervertebral disk (IVD) degeneration, and predominant clinical symptoms observed in degenerative disk disease (DDD).Overview of ...
Takeshi Sainoh +20 more
doaj +1 more source
BMC Veterinary Research, 2012 Background Disk-associated cervical spondylomyelopathy (DA-CSM) is a multifactorial neurological disorder in which progressive caudal cervical spinal cord compression is mainly caused by one or more intervertebral disk protrusions.
De Decker Steven +4 more
doaj +1 more source
Intervertebral disk regeneration in a rat model by allopurinol–loaded chitosan/alginate hydrogel
Biomolecules & Biomedicine, 2023 Intervertebral disk degeneration remains one of the most challenging health problems. In the current study, allopurinol was loaded into the chitosan nanoparticles and then incorporated into chitosan/alginate hydrogels and then further studied for its ...
Linhui Ye, Zengxin Gao, Saeed Rohani
doaj +1 more source
Frontiers in Neuroscience, 2021 To study the effect of intradiscal injection of simvastatin on discogenic pain in rats and its possible mechanism, 30 adult female rats were used in this experiment.
Xiaodong Huang +7 more
doaj +1 more source