Results 91 to 100 of about 34,930 (276)

Knockdown of asporin affects transforming growth factor-β1-induced matrix synthesis in human intervertebral annulus cells

Journal of Orthopaedic Translation, 2016
Background/Objective: Asporin is associated with osteoarthritis and lumbar disk degeneration. Previous studies in chondrocytes showed that asporin can bind to transforming growth factor-β1 (TGF-β1) and downregulate matrix biosynthesis.
Xu Jiang, Cheng Ai Wu, Ying Wang, Ke-Jian Shi, Xiao-Zhou Jiang, Shan Zheng, Wei Tian   +6 more
doaj   +1 more source

Apoptosis in Displaced Temporomandibular Joint Disc with and without Reduction: An Immunohistochemical Study [PDF]

, 2011
Internal derangement (ID) of the temporomandibular joint (TMJ) is due to an abnormal relationship of the articular disc to the mandibular condyle, glenoid fossa and articular eminence.
Almeida, Luis Eduardo, Leonardi, Rosalia, Loreto, Carla, Trevilatto, Paula C.   +3 more
core   +2 more sources

A LONG-TERM OUTCOMES OF LUMBAR DISK ARTHROPLASTY AND LUMBAR INTERBODY FUSION IN SURGICAL TREATMENT OF LUMBAR INTERVERTEBRAL DISK DEGENERATIVE DISEASE: A SYSTEMATIC REVIEW

Байкальский медицинский журнал
Relevance. Patients with long-standing discogenic low back pain who do not show clinical improvement after conservative treatment are referred for surgical treatments such as lumbar fusion or total disc arthroplasty.The purpose –– to evaluate the long ...
Ivan A. Stepanov, Vladimir A Beloborodov
doaj   +1 more source

Developmental adaptations to gravity in animals [PDF]

Terrestrial animals have adapted to a constant gravitational stress over millions of years. Tissues of the cardiovascular system and lumbar spine in tall species of animals such as the giraffe are particularly well adapted to high and variable vectors of
Hargens, Alan R.
core   +1 more source

Stiffening of the nucleus pulposus upon axial loading of the intervertebral disc: An experimental in situ study

JOR Spine, 2018
Mechanical loading is inherently related to the function and degeneration of the intervertebral disc. We present a series of experiments aimed at measuring the effect of a loading/unloading cycle of the intervertebral disc on the mechanical properties of
Steven V. Beekmans, Kaj S. Emanuel, Theodoor H. Smit, Davide Iannuzzi   +3 more
doaj   +1 more source

A Model for Intervertebral Disk Shape Variation in a Population Including the Effect of Degeneration [PDF]

, 2012
Edward J. Vresilovic, John Peloquin, Jonathon H. Yoder, Nathan T. Jacobs, S. Moon, Alexander C. Wright, Dawn M. Elliott   +6 more
openalex   +1 more source

Cell Therapy with Human Dermal Fibroblasts Enhances Intervertebral Disk Repair and Decreases Inflammation in the Rabbit Model

Global Spine Journal, 2016
Study Design Pilot study using the rabbit model. Objective Low back pain is often associated with disk degeneration. Cell therapy for degenerating disks may promote tissue regeneration and repair.
A. Chee, Peng Shi, T. Cha, T. Kao, Shu-Hua Yang, Jun Zhu, Ding Chen, Yejia Zhang, H. An   +8 more
semanticscholar   +1 more source

Itaconate-loaded metal–organic framework (MOF) nanomedicine for the sustained treatment of intervertebral disk degeneration

APL Materials
Intervertebral disk degeneration (IVDD) is a major cause of spinal pathology and pain and can lead to disability in adults in severe cases. The medication against disk degeneration is limited due to the lack of therapeutic drugs and ineffective delivery ...
Haixin Song, Jianhua Li, Qibin Zhang, Bingjie Zheng, Changsheng Li, Yiran Wang, Jian Chen, Junhui Liu, Tao Wu, Xiaotian Yang, Xueqian Kong, Fengdong Zhao   +11 more
doaj   +1 more source

An In Situ Anti-Inflammatory Drug Delivery System for Intervertebral Disks [PDF]

, 2012
Inês Pereira, Mariana Barbosa, Raquel M. Gonçalves, Clodomir de Jesus Costa Pereira, M. Molinos   +4 more
openalex   +1 more source

Associations Between Anesthetic Variables and Functional Outcome in Dogs With Thoracolumbar Intervertebral Disk Extrusion Undergoing Decompressive Hemilaminectomy [PDF]

, 2017
Joe Fenn, Eric B. Laber, Kim Williams, C.A. Rousse, Peter J. Early, Christopher L. Mariani, Karen R. Muñana, Steven De Decker, Holger A. Volk, Natasha J. Olby   +9 more
openalex   +1 more source