Results 21 to 30 of about 23,944 (304)

Magnetic Resonance Imaging Signal Alterations in Paraspinal Muscles in Dogs with Acute Thoracolumbar Intervertebral Disk Extrusion

Frontiers in Veterinary Science, 2018
Muscle signal alteration detected on MRI is seen in diverse pathologic conditions. We observed signal alterations within the paraspinal muscles in dogs with acute thoracolumbar intervertebral disk extrusion.
Peter Trampus, Christine Goepfert, Monika Welle, Diana Henke, Franck Forterre, Daniela Schweizer-Gorgas   +5 more
doaj   +1 more source

Gene‐Hydrogel Microenvironment Regulates Extracellular Matrix Metabolism Balance in Nucleus Pulposus

Advanced Science, 2020
Gene therapy provides an ideal potential treatment for intervertebral disk degeneration by delivering synthetic microRNAs (miRNAs) to regulate the gene expression levels.
Wei Chen, Hao Chen, Dandan Zheng, Hongbo Zhang, Lianfu Deng, Wenguo Cui, Yuhui Zhang, Hélder A. Santos, Hongxing Shen   +8 more
doaj   +1 more source

Concept Development of a New Lumbar Intervertebral Disk Implant

MATEC Web of Conferences, 2017
Worldwide spinal cord injury incidence is rising, due to spikes in traffic incidences, violence and an increase in ageing population, prone to injuries. To satisfy an expanding market, a wide variety of spinal implantable devices are available.
Doicin Cristian-Vasile, Ulmeanu Mihaela-Elena, Frîncu Alexa-Sorina, Enache Vlad-Cristian   +3 more
doaj   +1 more source

Clinical and magnetic resonance imaging characterization of cervical spondylomyelopathy in juvenile dogs

Journal of Veterinary Internal Medicine, 2019
Background Cervical spondylomyelopathy (CSM) occurs because of compression of the cervical spinal cord, nerve roots, or both, usually affecting young adult to older large and giant breed dogs. Juvenile dogs are affected infrequently.
Marília de AlbuquerqueBonelli, Ronaldo C. daCosta   +1 more
doaj   +1 more source

Intervertebral Disk Degeneration: The Microenvironment and Tissue Engineering Strategies

Frontiers in Bioengineering and Biotechnology, 2021
Intervertebral disk degeneration (IVDD) is a leading cause of disability. The degeneration is inevitable, and the mechanisms are complex. Current therapeutic strategies mainly focus on the relief of symptoms, not the intrinsic regeneration of the ...
Yiming Dou, Xun Sun, Xinlong Ma, Xin Zhao, Qiang Yang   +4 more
doaj   +1 more source

Sericin/crocetin micro/nanoparticles for nucleus pulposus cells regeneration: An “active” drug delivery system

Frontiers in Pharmacology, 2023
Introduction: Initiation and progression of intervertebral disk degeneration are linked to oxidative stress, with reactive oxygen species being a key factor.
Elia Bari, Sara Perteghella, Giovanna Rassu, Elisabetta Gavini, Giacomo Luigi Petretto, Maria Cristina Bonferoni, Paolo Giunchedi, Maria Luisa Torre   +7 more
doaj   +1 more source

Case report: Double adjacent ventral slot in two medium-sized breed dogs

Frontiers in Veterinary Science
Two medium-sized, 7-year-old dogs, with no previous history of pain, presented with acute neurologic symptoms consistent with intervertebral disk disease. Both cases had CT, where cervical pathology was identified.
Razvan Grigore Cojocaru, Bogdan Sicoe, Cristina Gaspar, Alexandra Grigoreanu, Gabriel Orghici, Ioan Tibru, Radu Lacatus   +6 more
doaj   +1 more source

Treatment of Intervertebral Disk Disease by the Administration of mRNA Encoding a Cartilage-Anabolic Transcription Factor

Molecular Therapy: Nucleic Acids, 2019
Intervertebral disk (IVD) degeneration is often associated with severity of lower back pain. IVD core is an avascular, highly hydrated tissue composed of type II collagen, glycosaminoglycans, and proteoglycans.
Chin-Yu Lin, Samuel Thomas Crowley, Satoshi Uchida, Yuji Komaki, Kazunori Kataoka, Keiji Itaka   +5 more
doaj   +1 more source

CT-Scan Based Evaluation of Dorsal-to-Ventral Ratios of Paraspinal Musculature in Chondrodystrophic and Non-chondrodystrophic Dogs

Frontiers in Veterinary Science, 2020
Objective: To assess and objectively quantify, with CT-scan exams, differences in cervical paraspinal musculature and vertebrae angulation that might influence the different predisposed sites for intervertebral disk disease observed in chondrodystrophic ...
Katinka Hartmann, Pia Düver, Stephan Kaiser, Carolin Fischer, Franck Forterre   +4 more
doaj   +1 more source

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

Advanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen, Chan Xue, Feifei Ni, Binwu Hu, Miaoheng Yan, He Zhang, Yuxiang Hu, Xiaoyao Peng, Guangfang Li, Yu Han, Hongjian Liu, Zengwu Shao, Qin Wang, Yulong Wei   +13 more
wiley   +1 more source