Results 21 to 30 of about 20,153 (223)
Coluna/Columna, 2011 OBJETIVOS: Este artigo tem por objetivo avaliar a presença de alterações do platô vertebral (Modic) e a sua associação com a instabilidade demonstrada nas radiografias em flexo-extensão e neutra no plano sagital. MÉTODOS: Análise seccional dos estudos de
Leandro Medeiros da Costa +3 more
doaj +1 more source
Advanced Science, EarlyView.This work identifies M1 macrophage‐mediated inflammation as a key driver of BMSC senescence and bone microstructural deterioration at the enthesis. A tissue‐adhesive hydrogel delivering senomorphic small extracellular vesicles suppresses this inflammatory‐senescent cascade and enhances BMSC resilience by inhibiting the cGAS‐STING‐NF‐κB pathway.
Lingzhi Kong +8 more
wiley +1 more source
Coluna/Columna, 2010 INTRODUÇÃO: a hérnia de disco lombar (HDL) é uma patologia prevalente na atualidade, que acarreta limitações físicas, psiquícas e sociais ao paciente.
Asdrubal Falavigna +6 more
doaj +1 more source
Advanced Science, EarlyView.Current technologies for spinal cord optogenetic stimulation rely on external power sources and face reliability constraints in freely behaving animals. Here, a fully implantable, battery‐powered optoelectronic device is introduced, enabling operation in any selected environment with wireless recharging for months‐long stimulation.
Shahriar Shalileh +8 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo +11 more
wiley +1 more source
Coluna/Columna, 2010 A seleção e o agendamento temporal inadequados dos pacientes permanecem as causas mais importantes de insucesso da cirurgia discal lombar. OBJETIVO: Este trabalho pretende avaliar os resultados clínicos e os factores preditivos que influenciam o ...
Paulo Jorge Da Rocha Carvalho +5 more
doaj +1 more source
A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair
Advanced Science, EarlyView.A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao +14 more
wiley +1 more source
Enabling Metal‐Based Soft Robotics Through Investment Casting
Advanced Intelligent Systems, EarlyView.Vacuum investment casting enables manufacturing of compliant soft robotic structures out of AA7075 high‐strength aluminum alloy. Additively manufactured patterns are converted into metal soft robotic structures addressing long lasting challenges like durability and nonlinearity of elastomer‐based soft robotics.
Felix Pancheri, Tim C. Lueth, Yilun Sun
wiley +1 more source
Transitory paraplegia due to a calcificated thoracic disc herniation [PDF]
Einstein (São Paulo), 2007 Thoracic disc herniation is rare and its clinical signs differ widely fromthose of cervical and lumbar disc hernias. The anterior approach is theclassical treatment for these cases.
Hallim Feres Junior +3 more
doaj
Animal Models and Experimental Medicine, EarlyView.In the compression suture group, a 5‐mm‐wide tail skin was removed, and then the defect was sutured to apply compressive force to the intervertebral disc. In the sham group, only the 5‐mm‐wide tail skin was removed without a compression suture. Compression suturing triggers apoptosis, inflammatory response, and imbalance of extracellular matrix ...
Xuening Liu +4 more
wiley +1 more source