Results 111 to 120 of about 4,715,032 (336)

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

Exploring amyotrophic lateral sclerosis patients’ experiences of psychological distress during the disease course in China: a qualitative study

open access: yesBMJ Open
Objective This study aims to explore the psychological distress course of Chinese amyotrophic lateral sclerosis (ALS) patients after the onset of the disease and to provide targeted nursing guidance.Design The interview content was analysed qualitatively.
Fen Yang   +7 more
doaj   +1 more source

A Transversal and Integrative Analysis of Exercise: A Study with Physical Activity Practitioners

open access: yesMotricidade, 2018
This study was done with individuals that practiced exercise and had two main objectives: (a) understand the importance of psychological factors in the process of adoption and maintenance of exercise behavior; and (b) analyze exercise behavior by ...
Rita Morais, Rui Gomes
doaj   +1 more source

Patient-reported depression measures in cancer: a meta-review [PDF]

open access: yes, 2015
The patient-reported depression measures that perform best in oncology settings have not yet been identified. We did a meta-review to integrate the findings of reviews of more than 50 depression measures used in adults with, or recovering from, any type ...
Andersen   +66 more
core   +1 more source

The Microbiota Shapes Central Nervous System Myelination in Early Life

open access: yesAdvanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch   +13 more
wiley   +1 more source

Development of depression detection algorithm using text scripts of routine psychiatric interview

open access: yesFrontiers in Psychiatry
BackgroundA psychiatric interview is one of the important procedures in diagnosing psychiatric disorders. Through this interview, psychiatrists listen to the patient’s medical history and major complaints, check their emotional state, and obtain clues ...
Jihoon Oh   +11 more
doaj   +1 more source

Psychosocial factors linked to the occupational psychological health of police officers: Preliminary study

open access: yesCogent Psychology, 2018
In the literature, the police environment is considered to be in a category of jobs with a high level of stress. More and more police officers are at work for stress-related psychological health problems. It is possible that the work functions associated
Andrée-Ann Deschênes   +2 more
doaj   +1 more source

Results From the Long-Term Inmate Survey: Focus on Child Abuse Histories [PDF]

open access: yes, 1998
This report of long-term inmates in Alaska correctional facilities attempts to describe the childhood experiences of a sample of long-term inmates, address the "cycle of abuse" issue; and present the correlates of abuse which may impact the pattern of ...
Barnes, Allan R.   +2 more
core  

Post- and peritraumatic stress in disaster survivors: An explorative study about the influence of individual and event characteristics across different types of disasters [PDF]

open access: yes, 2012
Background: Examination of existing research on posttraumatic adjustment after disasters suggests that survivors’ posttraumatic stress levels might be better understood by investigating the influence of the characteristics of the event experienced on ...
Alexander D   +12 more
core   +2 more sources

Acetylation Regulates ACSL4 Degradation Through Chaperone‐Mediated Autophagy to Alleviate Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu   +10 more
wiley   +1 more source

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