Results 51 to 60 of about 3,098,056 (351)

The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee   +16 more
wiley   +1 more source

Identifying characteristic features of community orientation among community health nurses in Fiji

open access: yesNursing Open, 2019
Aim The present study aimed to identify detailed characteristics of community orientation among community health nurses in Fiji. Design Qualitative descriptive design using semi‐structured individual interviews.
Sachiko Tanabe   +3 more
doaj   +1 more source

Applying Bayesian Hierarchical Probit Model to Interview Grade Evaluation [PDF]

open access: yesarXiv, 2020
Job interviews are a fundamental activity for most corporations to acquire potential candidates, and for job seekers to get well-rewarded and fulfilling career opportunities. In many cases, interviews are conducted in multiple processes such as telephone interviews and several face-to-face interviews.
arxiv  

"GAN I hire you?" -- A System for Personalized Virtual Job Interview Training [PDF]

open access: yesarXiv, 2022
Job interviews are usually high-stakes social situations where professional and behavioral skills are required for a satisfactory outcome. Professional job interview trainers give educative feedback about the shown behavior according to common standards.
arxiv  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

The anterior nucleus of the thalamus plays a role in the epileptic network

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 2010-2024, December 2022., 2022
Abstract Objectives We investigated both the metabolic differences and interictal/ictal discharges of the anterior nucleus of the thalamus (ANT) in patients with epilepsy to clarify the relationship between the ANT and the epileptic network. Methods Nineteen patients with drug‐resistant epilepsy who underwent stereoelectroencephalography were studied ...
Hao Yan   +9 more
wiley   +1 more source

„Existau temeri mari față de acest învățământ universitar privat” [PDF]

open access: yesPolis: Revista de Stiinte Politice, 2021
Interview by Doru ...
Doru TOMPEA
doaj  

Pragmatic Estimation of Sample Size for Number of Interviews for PRO development in the 2009 FDA PRO guidance [PDF]

open access: yesarXiv, 2023
PROs developed de novo, using the FDA guidance may involve structured patient interviews or focus groups. Qualitative Research is a methodology for eliciting and coding interviews and produces concepts or themes. These concepts are used to develop items in a PRO for use as an endpoint in Clinical trials. A convention in the field is that interviews and
arxiv  

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

open access: yesMolecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh   +6 more
wiley   +1 more source

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