Results 41 to 50 of about 1,511,334 (265)

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Therapists and the Topic of Meaning in Life in Their Encounters With Adolescents With Developmental Trauma: A Qualitative Study

open access: yesFrontiers in Psychiatry, 2022
BackgroundMeaning in life is important to achieve quality of life, psychological well-being and good mental health. Existential issues such as meaning in life have limited attention in mental health care and treatment for children and young people in ...
Kjersti Olstad   +4 more
doaj   +1 more source

Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe

open access: yesMolecular Oncology, EarlyView.
Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns   +4 more
wiley   +1 more source

Czech language acquisition seen by a Russian-speaking learner

open access: yesВестник Северо-Кавказского федерального университета, 2022
The paper discusses teaching Czech language to Russian speaking adolescent learners. The article is based on a research which focuses on the learners´ subjective perception of their second language acquisition. The topic, i. e.
J. Kovářová
doaj   +1 more source

Was your father a problem drinker?

open access: yesJournal of Comparative Social Work, 2009
In this article, the challenges of carrying out life story interview research on the adult sons of problem-drinking fathers will be discussed. Earlier studies have shown that parents’ problem drinking can disturb family life and be harmful in various ...
Henna Pirskanen
doaj   +1 more source

Understanding Generative AI in Art: An Interview Study with Artists on G-AI from an HCI Perspective [PDF]

open access: yesarXiv, 2023
The emergence of Generative Artificial Intelligence (G-AI) has changed the landscape of creative arts with its power to compose novel artwork and thus brought ethical concerns. Despite the efforts by prior works to address these concerns from technical and societal perspectives, there exists little discussion on this topic from an HCI point of view ...
arxiv  

Geometric and dosimetric evaluation of a commercial AI auto‐contouring tool on multiple anatomical sites in CT scans

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Current radiotherapy practices rely on manual contouring of CT scans, which is time‐consuming, prone to variability, and requires highly trained experts. There is a need for more efficient and consistent contouring methods. This study evaluated the performance of the Varian Ethos AI auto‐contouring tool to assess its potential integration into
Robert N. Finnegan   +6 more
wiley   +1 more source

Toward a human‐centric co‐design methodology for AI detection of differences between planned and delivered dose in radiotherapy

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Introduction Many artificial intelligence (AI) solutions have been proposed to enhance the radiotherapy (RT) workflow, but limited applications have been implemented to date, suggesting an implementation gap. One contributing factor to this gap is a misalignment between AI systems and their users.
Luca M. Heising   +11 more
wiley   +1 more source

The Impact of Digitalization in the HR Department: A Post-Pandemic Qualitative Analysis [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2022
The impact digitalization has on organizations has been a topic of interest for many years and will continue to be due to its complexity. As long as digitalization evolves, so will organizations, and there will always be new areas to uncover.
Oana-Cristina Datcu   +2 more
doaj  

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