Results 51 to 60 of about 1,270,083 (346)
The use of semi-structured interviews for the characterisation of farmer irrigation practices
, 2015 . For the development of sustainable and realistic water security, generating information on the behaviours, characteristics, and drivers of users, as well as on the resource itself, is essential.
J. O'Keeffe +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Testing like you teach: The challenge of constructing local, ecologically valid tests [PDF]
, 2008 In an educational context, local, ecologically valid tests can reflect the use of literacy and thinking tools. These tests present a challenge to central, content focused, high-stakes testing, and to transmission approaches to teaching.
Whitehead, David
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Guilty Pleas or Trials: Which Does the Barrister Prefer? [PDF]
, 2008 Barristers in England and attorneys in the United States have been upbraided for pursuing their interests to their clients\u27 detriment in recommending guilty pleas over trials.
Tague, Peter W.
core +1 more source
Under-explicit and minimally explicit reference: Evidence from a longitudinal case study [PDF]
, 2020 This chapter reports on a 2 ½ year longitudinal case study of one Korean speaker of English, focusing on the development of her command of accessibility marking in referring to persons.
Ryan, Jonathon
core
Nursing home residents’ perspectives on oral health: An in-depth interview study
International Journal of Nursing Studies AdvancesBackground: Oral health is associated with general health and care dependency, but is often neglected in nursing homes. Integration of oral care into general care is necessary, but is hampered by multiple barriers at different levels.
Patricia A․ I․ Vandenbulcke +8 more
doaj +1 more source
Was your father a problem drinker?
Journal of Comparative Social Work, 2009 In this article, the challenges of carrying out life story interview research on the adult sons of problem-drinking fathers will be discussed. Earlier studies have shown that parents’ problem drinking can disturb family life and be harmful in various ...
Henna Pirskanen
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source