Results 41 to 50 of about 186,734 (260)

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier   +11 more
wiley   +1 more source

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas   +3 more
wiley   +1 more source

Understanding the physical, social, and emotional experiences of people with uncontrolled Type 2 diabetes: a qualitative study

open access: yesPatient Preference and Adherence, 2016
Anna Berenguera,1,2,* Àngels Molló-Inesta,1,3,4,* Manel Mata-Cases,1,4–6 Josep Franch-Nadal,1,2,6–8 Bonaventura Bolíbar,1 Esther Rubinat,1,9,10 Dídac Mauricio1,11 1Scientific Department, Institut Universitari d ...
Berenguera A   +6 more
doaj  

The Impact of Digitalization in the HR Department: A Post-Pandemic Qualitative Analysis [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2022
The impact digitalization has on organizations has been a topic of interest for many years and will continue to be due to its complexity. As long as digitalization evolves, so will organizations, and there will always be new areas to uncover.
Oana-Cristina Datcu   +2 more
doaj  

Administering Blinatumomab via Continuous Intravenous Infusion in Pediatric Patients—A Single‐Institution Retrospective Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab, a CD19xCD3 bispecific T‐cell engager, has become standard therapy for children with de novo B‐cell acute lymphoblastic leukemia (B‐ALL). This retrospective review describes the experience of blinatumomab administration in pediatric patients.
Julia M. Hurley   +6 more
wiley   +1 more source

Validity and reliability of the persian version of the modified telephone interview for cognitive status among community-dwelling older adults in Iran

open access: yesDementia & Neuropsychologia
. Due to the increase in the population of the elderly, there is a growing trend in some diseases such as cognitive disorders (dementia) which are common in this era, and the diagnosis and treatment of this disease are still facing challenges. Therefore,
Fatemeh Ghonoodi   +4 more
doaj   +1 more source

Secretory Phospholipase A2 in Patients With Sickle Cell Disease Hospitalized for Vaso‐Occlusive Pain Episodes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Secretory phospholipase A2 (sPLA2) is an inflammatory mediator linked to acute chest syndrome (ACS) in sickle cell disease (SCD), a serious complication that can develop during an acute vaso‐occlusive pain episode (VOE). Plasma sPLA2 levels have been proposed as a potential biomarker for predicting ACS onset.
Rawan Korman   +10 more
wiley   +1 more source

Desafios nas entrevistas de uma investigação qualitativa: Relato de experiência Desafíos en las entrevistas de una investigación cualitativa: Relato de experiencia Qualitative research interview challenges: Experience report

open access: yesInvestigación y Educación en Enfermería, 2011
Relato das percepções surgidas da experiência da recolha dos dados da investigação qualitativa "Representações Sociais da Internação Domiciliar na terminalidade: o olhar do cuidador familiar".
Stefanie Griebeler Oliveira   +5 more
doaj  

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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