Results 71 to 80 of about 2,592,772 (309)

Pathophysiological Mechanisms of Emaciation Syndrome in Plectropomus leopardus: Insights From Histology and Transcriptomics

open access: yesAnimal Research and One Health, EarlyView.
Integrated phenotypic, histological, transcriptomic, and validation analyses reveal that emaciation syndrome in Plectropomus leopardus is associated with intestinal structural damage, hepatic metabolic remodeling, and muscle protein degradation, highlighting coordinated multi‐tissue alterations underlying disease progression.
Zhihao Zhang   +11 more
wiley   +1 more source

Saving lives and protecting people from parasitic diseases [PDF]

open access: yes
Parasitic diseases, including malaria and neglected tropical diseases (NTDs), causedevastating illness and economic burden among millions of people around the world and in theUnited States, threatening local populations, businesses, travelers, and ...

core  

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva   +8 more
wiley   +1 more source

Working to reduce parasitic diseases in the United States [PDF]

open access: yes
Parasitic diseases not only affect people globally, they also affect many people in the United States. CDC works with partners to reduce parasitic diseases both within the United States and globally by:\u2022 Conducting public health surveillance to ...

core  

Health-related quality of life among school children with parasitic infections : findings from a national cross-sectional survey in Côte d'Ivoire [PDF]

open access: yes, 2014
Parasitic infections are still of considerable public health relevance, notably among children in low- and middle-income countries. Measures to assess the magnitude of ill-health in infected individuals, however, are debated and patient-based proxies ...
Silué, Kigbafori D.   +32 more
core   +1 more source

Pharmacometric evaluation of pre‐referral rectal artesunate in children with severe malaria

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Parenteral artesunate is the preferred first‐line treatment for severe malaria. Pre‐referral rectal artesunate suppositories are recommended where parenteral treatment is inaccessible. In this study, we compared dihydroartemisinin exposure and model‐predicted early parasite clearance following rectal artesunate and intravenous artesunate in ...
Ayorinde Adehin   +6 more
wiley   +1 more source

Prevalence and factors associated with intestinal parasitic infection among under-five children in and around Haro Dumal Town, Bale Zone, Ethiopia

open access: yesBMC Pediatrics, 2019
Background Intestinal parasitic infection is diversified illness and diseases caused millions morbidity among under-five children lives in developing countries particularly vulnerable rural communities. Deworming coverage in such community is low.
Eshetu Gadisa, Kefiyalew Jote
doaj   +1 more source

Challenges and Future Directives of Synthetic Biology in Engineering Plant–Microbe Partnerships for Sustainable Agriculture

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Synthetic biology has recently proven to be a valuable tool for enhancing agriculture even in the face of environmental and biological stresses. Understanding the challenges that militate synthetic biology will assist in ensuring safe, stable, and scalable crop production.
Ben Jesuorsemwen Enagbonma   +6 more
wiley   +1 more source

Effect of Environmental Modification and Renewal on Prevalence of Parasitic Infections Among Primary School Pupils in Esan West Local Government Area of Edo State, Nigeria

open access: yesSokoto Journal of Medical Laboratory Science, 2017
Intestinal parasitic infections constitute a global public health challenge particularly among primary school pupils in developing countries. A total of 444 stool samples were collected from pupils aged 3 to 16 years in 2 urban and 2 rural primary ...
Jemikalajah, Daniel Johnson
doaj  

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

open access: yesBMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng   +4 more
wiley   +1 more source

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