Results 141 to 150 of about 9,797,826 (264)

Role of intestinal microbiota and metabolites on gut homeostasis and human diseases

open access: yesBMC Immunology, 2017
A vast diversity of microbes colonizes in the human gastrointestinal tract, referred to intestinal microbiota. Microbiota and products thereof are indispensable for shaping the development and function of host innate immune system, thereby exerting ...
Lan Lin, Jianqiong Zhang
semanticscholar   +1 more source

Probiotics and Intestinal Diseases [PDF]

open access: yesAnnals of Nutrition and Metabolism, 2010
Philip Rosenstiel, Eduard F. Stange
openaire   +3 more sources

Sleeve gastrectomy ameliorates renal injury in obesity-combined hyperuricemic nephropathy mice by modulating the AMPK/Nrf2/ABCG2 pathway

open access: yesScientific Reports
Hyperuricemic nephropathy (HN) is renal injury caused by hyperuricemia (HUA). While sleeve gastrectomy (SG) has shown promise in improving renal injury in patients with obesity-related HN, the mechanisms are not fully understood.
Ke Song   +10 more
doaj   +1 more source

A new recurrent neural network based predictive model for Faecal Calprotectin analysis: A retrospective study [PDF]

open access: yesarXiv, 2016
Faecal Calprotectin (FC) is a surrogate marker for intestinal inflammation, termed Inflammatory Bowel Disease (IBD), but not for cancer. In this retrospective study of 804 patients, an enhanced benchmark predictive model for analyzing FC is developed, based on a novel state-of-the-art Echo State Network (ESN), an advanced dynamic recurrent neural ...
arxiv  

Roles for Intestinal Bacteria, Viruses, and Fungi in Pathogenesis of Inflammatory Bowel Diseases and Therapeutic Approaches.

open access: yesGastroenterology, 2017
Intestinal microbiota are involved in the pathogenesis of Crohn's disease, ulcerative colitis, and pouchitis. We review the mechanisms by which these gut bacteria, fungi, and viruses mediate mucosal homeostasis via their composite genes (metagenome) and ...
R. Sartor, Gary D. Wu
semanticscholar   +1 more source

Diabetes is predominantly an intestinal disease

open access: yesIndian Journal of Endocrinology and Metabolism, 2013
Diabetes mellitus (DM) is a chronic, progressive, medically incurable disease and is poorly controlled in a vast majority, in spite of tremendous advancements in pharmacotherapy. Altered gut microbiome can predict diabetes. There is strong and consistent evidence regarding role of the gut and many gut hormones like incretins in energy and glucose ...
openaire   +4 more sources

Tight Junction in the Intestinal Epithelium: Its Association with Diseases and Regulation by Phytochemicals

open access: yesJournal of Immunological Research, 2018
The intestine plays an essential role in integrating immunity and nutrient digestion and absorption. Adjacent intestinal epithelia form tight junctions (TJs) that are essential to the function of the physical intestinal barrier, regulating the ...
Bonggi Lee, K. Moon, C. Kim
semanticscholar   +1 more source

Tumour Necrosis Factor Alpha in Intestinal Homeostasis and Gut Related Diseases

open access: yesInternational Journal of Molecular Sciences, 2019
The intestinal epithelium constitutes an indispensable single-layered barrier to protect the body from invading pathogens, antigens or toxins. At the same time, beneficial nutrients and water have to be absorbed by the epithelium.
Barbara Ruder, R. Atreya, C. Becker
semanticscholar   +1 more source

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