Results 151 to 160 of about 9,797,826 (264)

Intestine‐Specific Expression of Human Chimeric Intestinal Alkaline Phosphatase Attenuates Western Diet‐Induced Barrier Dysfunction and Glucose Intolerance [PDF]

open access: yes, 2018
Intestinal epithelial cell derived alkaline phosphatase (IAP) dephosphorylates/detoxifies bacterial endotoxin lipopolysaccharide (LPS) in the gut lumen.
Ghosh, Shobha   +5 more
core   +1 more source

Sirtuin2 suppresses the polarization of regulatory T cells toward T helper 17 cells through repressing the expression of signal transducer and activator of transcription 3 in a mouse colitis model

open access: yesImmunity, Inflammation and Disease
Introduction Regulatory T cells (Tregs) play an important role in inflammatory bowel diseases (IBDs) through modulating intestinal inflammation. However, the factors affecting Treg function and plasticity during IBD progression are not thoroughly ...
Liuqing Ge   +7 more
doaj   +1 more source

To explore the postoperative nutritional status and factors influencing prognosis in patients with chronic constipation complicated by malnutrition

open access: yesFrontiers in Medicine
BackgroundMany patients with constipation also suffer from varying degrees of malnutrition, and the relationship between the two conditions is a vicious cycle.
Le Wang   +22 more
doaj   +1 more source

UMMAN: Unsupervised Multi-graph Merge Adversarial Network for Disease Prediction Based on Intestinal Flora [PDF]

open access: yesarXiv
The abundance of intestinal flora is closely related to human diseases, but diseases are not caused by a single gut microbe. Instead, they result from the complex interplay of numerous microbial entities. This intricate and implicit connection among gut microbes poses a significant challenge for disease prediction using abundance information from OTU ...
arxiv  

Nucleotide 9-mers Characterize the Type II Diabetic Gut Metagenome [PDF]

open access: yesarXiv, 2015
Discoveries of new biomarkers for frequently occurring diseases are of special importance in today's medicine. While fully developed type II diabetes (T2D) can be detected easily, the early identification of high risk individuals is an area of interest in T2D, too.
arxiv  

The Eph/ephrin system symphony of gut inflammation

open access: yesPharmacological Research, 2023
The extent of gut inflammation depends largely on the gut barrier’s integrity and enteric neuroimmune interactions. However, the factors and molecular mechanisms that regulate inflammation-related changes in the enteric nervous system (ENS) remain ...
Peishan Qiu   +9 more
doaj  

Gastrointestinal pan-cancer landscape of tumor matrix heterogeneity identifies biologically distinct matrix stiffness subtypes predicting prognosis and chemotherapy efficacy

open access: yesComputational and Structural Biotechnology Journal, 2023
Gastrointestinal (GI) cancers are a heterogeneous group of primary solid tumors, arising in GI tract from the esophagus to rectum. Matrix stiffness (MS) is a critical physical factor for cancer progression; however, its importance in tumor progression ...
Yumei Ning   +8 more
doaj  

Serum 1,3-Beta-D-Glucan Values During and After Laparoscopic and Open Intestinal Surgery. [PDF]

open access: yes, 2018
Background1,3-beta-D Glucan (BDG) assay has good accuracy for distinguishing patients with invasive fungal infections from patients without. Some procedures and medications affect BDG levels, resulting in false-positive BDG results.
Berger, Anton   +11 more
core  

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